Effect of yoga on cardiovascular risks in sons, daughters, sisters and brothers of hypertensives and type 2 diabetics

Recruiting

Conditions: Subjects who have the family history of Diabetes, Hypertension or Both

Registration Number: CTRI/2017/03/008208

Lead Sponsor: Jawaharlal Institute of Post graduate Medical Education and Research JIPMER

Brief Summary: This study is an interventional, comparative study assessing the effect of yoga practice on cardiovascular risks in 180 participants who are healthy first degree relatives (sons, daughters, sisters and brothers) of hypertensives and type 2 diabetics compared to 60 control subjects (healthy subjects who are NOT first degree relatives of hypertensives and type 2 diabetics). The study will be conducted in one year in JIPMER Hospital, Puducherry, India.

The primary outcome i.e., blood pressure and the secondary outcomes like cardiovascular autonomic functions, fasting blood glucose, insulin resistance, lipid risk factors, Inflammatory markers (hsCRP, IL-6, Homocysteine, Adiponectin, TNF-alpha), endothelial marker (vWF), total oxidant level, and anti-oxidant level (total anti-oxidant status) will be recorded before and after 12weeks of yoga therapy.

Detailed Description: Not available

Recruitment & Eligibility

Status: Open to Recruitment

Sex: All

Target Recruitment: 240

Inclusion Criteria

Adult males and females of age 18 -40 years, who are first degree relatives (sons, daughters, sisters and brothers) of hypertensives or diabetics or both, who have been under therapy for at least one year.

Exclusion Criteria

Subjects, who are Diabetics, Hypertensives, Alcoholics, Sportspersons, receiving hormonal therapy, severe Kidney diseases and other endocrine disorders, will be excluded from the study.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Twelve weeks of yoga therapy is expected to reduce the blood pressure in first degree relatives of hypertensives and diabetics	Twelve weeks of yoga therapy is expected to reduce the blood pressure in first degree relatives of hypertensives and diabetics

Secondary Outcome Measures

Name	Time	Method
improve cardiovascular autonomic functions,	reduce fasting blood glucose,

Trial Locations

Locations (1): Jawaharlal Institute of Post graduate Medical Education and Research (JIPMER)
🇮🇳
Pondicherry, PONDICHERRY, India
Jawaharlal Institute of Post graduate Medical Education and Research (JIPMER)
🇮🇳Pondicherry, PONDICHERRY, India
Dr Gopal Krushna Pal
Principal investigator
drgkpal@gmail.com