Effect of yoga on cardiovascular risks in first degree relatives of hypertensives and type 2 diabetics
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 240
- 试验地点
- 1
- 主要终点
- Twelve weeks of yoga therapy is expected to reduce the blood pressure in first degree relatives of hypertensives and diabetics
研究概览
简要总结
This study is an interventional, comparative study assessing the effect of yoga practice on cardiovascular risks in 180 participants who are healthy first degree relatives (sons, daughters, sisters and brothers) of hypertensives and type 2 diabetics compared to 60 control subjects (healthy subjects who are NOT first degree relatives of hypertensives and type 2 diabetics). The study will be conducted in one year in JIPMER Hospital, Puducherry, India.
The primary outcome i.e., blood pressure and the secondary outcomes like cardiovascular autonomic functions, fasting blood glucose, insulin resistance, lipid risk factors, Inflammatory markers (hsCRP, IL-6, Homocysteine, Adiponectin, TNF-alpha), endothelial marker (vWF), total oxidant level, and anti-oxidant level (total anti-oxidant status) will be recorded before and after 12weeks of yoga therapy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- All
入选标准
- •Adult males and females of age 18 -40 years, who are first degree relatives (sons, daughters, sisters and brothers) of hypertensives or diabetics or both, who have been under therapy for at least one year.
排除标准
- •Subjects, who are Diabetics, Hypertensives, Alcoholics, Sportspersons, receiving hormonal therapy, severe Kidney diseases and other endocrine disorders, will be excluded from the study.
结局指标
主要结局
Twelve weeks of yoga therapy is expected to reduce the blood pressure in first degree relatives of hypertensives and diabetics
时间窗: Twelve weeks of yoga therapy is expected to reduce the blood pressure in first degree relatives of hypertensives and diabetics
次要结局
- improve cardiovascular autonomic functions,(reduce fasting blood glucose,)