Research on the Efficacy Mechanism of Natural Psychotherapy for Neurosis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 80
- 试验地点
- 3
- 主要终点
- Obsessive-compulsive symptoms
研究概览
简要总结
explore objective indicators of the efficacy of natural psychotherapy in the treatment of disorders such as obsessive-compulsive disorder
详细描述
- To evaluate the cognitive function, Cognitive control, emotion and other aspects of neurosis patients, and to understand and master the cognitive behavior indicators of this population.
- Investigate the pathological mechanism of neurotic patients from the aspects of EEG/fMRI and biology.
- To investigate the therapeutic effect of natural psychotherapy on cognitive impairment and related mood, sleep and symptom intervention in neurotic patients. In order to achieve the symptoms of neurosis patients, cognitive impairment and related mood and sleep intervention and promotion, while providing a scientific basis for neurosis rehabilitation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
盲法说明
The patient was assigned to either the intervention group or the control group, but the control group would also receive treatment after a two-month waiting period. Therefore, the patient was only informed whether they would be participating in the first or second intervention.
入排标准
- 年龄范围
- 16 Years 至 55 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •were between 16 and 55 years old;
- •were diagnosed with OCD by an experienced psychiatrist utilizing the Structured Clinical Interview for DSM-5 (SCID);
- •had an illness duration of at least 12 months;
- •were able to participate in the entire trial and face-to-face on-site assessment
排除标准
- •pregnant or breastfeeding;
- •suffered from organic brain diseases or severe physical illness;
- •had a history of substance or alcohol abuse
- •were at high risk of suicide
研究组 & 干预措施
Natural Psychotherapy
Intervention using natural psychotherapy for OCD patients for two to three hours once a week for eight weeks
干预措施: Natural Psychotherapy (Behavioral)
结局指标
主要结局
Obsessive-compulsive symptoms
时间窗: Baseline, week 4, week 8
Using the score of Yale-Brown Obsessive-Compulsive Scale as the primary outcome, a decrease in score of ≥35% was considered a 'response to treatment', also referred to as a 'full response', and a decrease in score of ≥25% was considered a 'partial response'
次要结局
- Self-reported obsessive-compulsive symptoms(Baseline, week 4, week 8)
- Cognitive inhibition(Baseline, week 8)
- Behavioral inhibition(Baseline, week 8)
- ERP components associated with cognitive function(Baseline, week 8)
- rest fMRI in Obsessive-compulsive patients(Baseline, week 8)
研究者
Xiang Yang Zhang
Professor
Beijing HuiLongGuan Hospital