NCT05699213招募中不适用
A Pilot Study Evaluating the Feasibility of Novel MRI Sequences and Blood-Based Biomarkers for Discriminating Nodules Found During Lung Cancer Screening
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Accrual and Retention Rate
研究概览
简要总结
The primary objective of this pilot observational study is to evaluate the accrual and retention rate of a study population from a centralized lung cancer screening program to support MRI and blood-based biomarker research for lung cancer screening.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Ability to read and understand informed consent
- •Male or female adults who are at high risk for lung cancer and are enrolled in the centralized lung cancer screening program: Based on USPSTF guidelines: Age 50-80 with 20 or greater pack-year smoking story who continue to smoke or quit within the past 15 years without sign or symptoms of lung cancer. Or based on National Comprehensive Cancer Network (NCCN) guidelines but do not meet the USPSTF guidelines, age 50-unlimited
- •Found to have one or more lung nodules that is 6mm or greater on screening LDCT
排除标准
- •Persons with an active diagnosis of cancer
- •Persons with active signs or symptoms of lung cancer
- •Persons with mechanically, magnetically, or electrically activated implants, such as cardiac pacemakers, neurostimulators, and infusion pumps.
- •Persons with ferromagnetic implants and ferromagnetic foreign bodies, such as intracranial aneurysm clips, shrapnel and intraocular metal chips as these could become dislodged.
- •Persons who are pregnant, nursing, are implanted with intrauterine devices (IUD's) that are not MR-compatible
- •Persons unable to tolerate MRI imaging secondary to an inability to lie supine or severe claustrophobia.
- •Persons who are non-compliant with visit instructions, including inability to lie still, hold breath or follow procedure instructions
结局指标
主要结局
Accrual and Retention Rate
时间窗: 3 years
The primary outcome measure is the accrual and retention rate of a study population from a centralized lung cancer screening program to support MRI and blood-based biomarker research.
次要结局
- Concordance of Nodule Features: Presence of Calcifications(3 years)
- Concordance of Size of Nodules(3 Years)
- Concordance of Nodule Features: Presence of Fat(3 years)
- Concordance of Nodule Features: Presence of Spiculations(3 years)
- Concordance of Nodule Features: Solid, Part Solid, Non-Solid(3 years)
研究者
Sara Ghandehari
Associate Professor
Cedars-Sinai Medical Center
研究点 (1)
Loading locations...
相似试验
Unknown
不适用
Feasibility of a Sleep Improvement Intervention for Weight Loss and Its Maintenance in Sleep Impaired Obese AdultsObesityNCT04243317Zayed University40
已完成
不适用
Light Therapy for Onychomycosis StudyOnychomycosis of ToenailNCT05139888ToeFX Inc.126
已完成
不适用
Innovations in Treating COPD Exacerbations: Pilot Project on Action Plans Using New Technology.COPDNCT02275078McGill University Health Centre/Research Institute of the McGill University Health Centre40
Unknown
不适用
A Trial of a Preventive Intervention Program for Chilean Families With Depressed ParentsDepressionNCT02593266University of Chile64
已完成
不适用
RESTORE-TAVI PilotFrailtyAortic StenosisNCT06121921Barts & The London NHS Trust40