Medical Imaging in Bladder Tumors by MRI

Recruiting

• Conditions: Bladder Tumor; Magnetic Resonance Imaging

• Registration Number: NCT06033040
• Lead Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Brief Summary

This study prospectively included 178 patients with bladder neoplastic lesions who planned to undergo surgery (with or without preoperative neoadjuvant chemotherapy). Inclusion criteria: Patients with pathologically confirmed bladder cancer after radical or partial cystectomy or TURBT (\< 2 weeks between surgical resection and imaging). Exclusion criteria: 1) Prior history of chemotherapy and/or radiotherapy; 2) No surgical resection; 3) The interval between surgical resection and imaging examination is \> 2 weeks; 4) Obvious artifacts; 5)MRI scan contraindications. All subjects underwent pelvic MRI. Data was collected using a Siemens VIDA 3TMR scanner (Siemens Healthcare, Erlangen, Germany). All subjects underwent standardized scanning protocols. The obtained images are post-processed and the experimental results are analyzed statistically.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-07-27
• Study Start: 2023-08-15
• Status Verified: 2023-09
• Study First Submitted QC: 2023-09-04
• Last Update Submitted: 2023-09-04
• Study First Posted: 2023-09-13
• Last Update Posted: 2023-09-13
• Primary Completion: 2025-12-31
• Study Completion: 2025-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 178

Inclusion Criteria

1. Clinical diagnosis of bladder neoplasm
2. Must undergo radical or partial cystectomy or TURBT surgery within 2 weeks between surgical resection and imaging

Exclusion Criteria

1. A history of pelvic radiotherapy or chemotherapy;
2. Lack of pathological findings or no surgery;
3. The interval between surgical resection and imaging examination > 2 weeks;
4. Poor image quality due to poor coordination or motion artifacts;
5. MRI scan contraindications

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
quantitative parameters by MRI	From the time the participants completed the MRI scan to the post-processing of the resulting images,assessed up to 2 months	quantitative parameters by functional MRI

Trial Locations

Locations (1)

Sun Yat-sen Memorial Hospital, Sun Yat-sen University; 🇨🇳 Guangzhou, Guang Dong, China