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A STUDY TO ASSESS THE SPECTRUM OF URINARY BACTERIAL ISOLATES AND THEIR ANTIBIOTIC SENSITIVITY AND RESISTANCE PATTERN IN PATIENTS WITH URINARY TRACT INFECTION ADMITTED IN THE INTENSIVE CARE UNIT OF A HOSPITAL

Completed
Conditions
Urinary tract infection, site notspecified,
Registration Number
CTRI/2022/03/041017
Lead Sponsor
SHAISTA AHMED
Brief Summary

The work up for urinary tract infections (UTIs) will include: urinalysis, Gram staining, and urine culture. The mode of collection of urine specimens will be noted: viz supra pubic aspiration, urethral catheterization, or midstream clean catch specimen .The threshold for establishing UTI will include finding 2-5 or more white blood cells (WBCs) or bacteria per high-power field (HPF) in a centrifuged urine sediment.In voided urine specimen, bacterial counts ≥100,000 CFU/mL will be considered diagnostic for a UTI .In catheterized specimens 10000 CFU/mL urines will be considered significant. In supra pubic aspiration specimen any concentration of CFU/mL will be counted as true UTI [6].Bacteriuria without pyuria suggests contamination or colonization and will not be included in the analysis. Organisms, isolated from clinical specimens, will be identified by culture using standard microbiological technique. In patients who are culture positive the demographic data, microrganism grown will be identified and sensitivity patterns of these organism will be seen. After that patient will be assessed on the basis of risk factors which are diabetes mellitus ,hypertension ,indwelling urinary catheter ,duration of ICU stay, Patients on any steroid, duration of antibiotics, coronary heart disease, chronic kidney disease,COPD,cancer,heart failure and surgical intervention.

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
100
Inclusion Criteria

All patients admitted to ICU diagnosed with UTI and a positive urine culture report with Pyuria.

Exclusion Criteria

Not provided

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To define the patterns of bacterial strains isolated in urine cultures of patients admitted insingle time point
the ICU setting with UTIsingle time point
and To define the antibiotic sensitivity patterns of the various bacterial strains of patients admitted in the ICU setting with UTIsingle time point
Secondary Outcome Measures
NameTimeMethod
To determine demographic characteristics of patients admitted in the ICU setting with UTI2. To analyze the potential risk factors associated with UTI in the ICU setting with UTI

Trial Locations

Locations (1)

FORTIS ESCORTS HEART INSTITUTE

🇮🇳

South, DELHI, India

FORTIS ESCORTS HEART INSTITUTE
🇮🇳South, DELHI, India
SHAISTA AHMED
Principal investigator
7011336971
Shaistaahmed97@gmail.com

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