DRKS00000319
Completed
未知
Prostagen Study - Investigation of polymorphisms in genes of the fatty acid metabolism in relation to the evolvement and further development of prostate cancer
Klinik für Tumorbiologie0 sites158 target enrollmentStarted: February 1, 2010Last updated:
Overview
- Phase
- 未知
- Status
- Completed
- Sponsor
- Klinik für Tumorbiologie
- Enrollment
- 158
Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
- Allocation
- Non-randomized controlled study
- Masking
- Open (masking not used)
Eligibility Criteria
- Ages
- 18 Years to one (—)
- Sex
- Male
Inclusion Criteria
- •Patient inclusion criteria:
- •\- Patients with histologically proven prostate cancer who are treated or advised in one of the centers involved in the study
- •\- Written informed consent
- •Inclusion criteria for healthy subjects:
- •\- Subjects without prostate cancer or any other tumor, which are screened in one of the study centers and are 70 years or older.
- •\- Exclusion of prostate cancer according to one of the following criteria:
- •\* Men with a PSA level of maximum 10 ng/ml, who underwent a 12x punch biopsy with a negative result.
- •\* Men with benign prostatic hyperplasia (BPH), in whom a transurethral resection of the prostate (TUR\-P) was conducted and the histology of the recovered material was negative (PSA maximum 10 ng /l).
- •\* PSA less than 4ng/l and no prostate cancer family history
- •\- Written informed consent
Exclusion Criteria
- •\- Patients / healthy subjects with a known allergy to seafood
- •\- Patients / healthy subjects who can not eat or are on a special diet
- •\- Patients / healthy subjects with malabsorption (i.e. after gastrointestinal surgery, inflammatory bowel disease)
- •\- Patients / healthy subjects with severe internal diseases, especially with impaired coagulation, liver or gall bladder disease, bile duct tumors, or pancreatitis
- •\- Patients / healthy subjects who are already taking omega\-3 fatty acids supplementation or other dietary supplements and drugs that are likely to affect the results of the research
- •\- Patients / healths subjects with psychiatric or CNS disorders, who are not able to consent to participation in the study
Investigators
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