跳至主要内容
临床试验/NCT02665780
NCT02665780撤回不适用

Assessing the Effect of Periodontal Debridement, Tongue Cleaning and Mouth Rinsing for the Treatment of Oral Malodour

University of British Columbia0 个研究点开始时间: 2017年10月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
撤回
主要终点
Reduction of oral malodour below threshold

研究概览

简要总结

This study evaluates the short and long term effect of dental cleaning and mouthrinsing for the treatment of bad breath

详细描述

The majority of bad breath producing bacteria can be found in pockets around the gums and the top of the tongue. It is generally agreed that one of the most effective means of controlling the production of bad breath gases from these bacteria is their mechanical removal. Tongue cleaning has shown consistent results in the reduction of bad breath, while dental cleaning has shown positive, but less conclusive results. The addition of a mouth rinse to mechanical measures has shown medium-term effectiveness, however there is currently no information available that describes the long-term impact of mechanical and chemical measures for the treatment of bad breath and the appropriate interval for follow-up and on-going management to prevent difficult cases.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

性别
All
接受健康志愿者
是

入选标准

  • •Organoleptic score of 2 or more, and volatile sulfur compound score of greater than 1.5ng/10ml of hydrogen sulfide and 0.5ng/10ml of methyl mercaptan

排除标准

  • •Moderate to severe periodontal disease, systemic illness or dental disease associated with halitosis, antibiotic use in the past month, need for antibiotic prophylaxis for dental procedures and current smokers

研究组 & 干预措施

Treatment

Experimental

Periodontal debridement, tongue cleaning, mouth rinsing with 20ml Cetylpyridium Chloride daily for 24 weeks

干预措施: Periodontal debridement (Procedure)

Treatment

Experimental

Periodontal debridement, tongue cleaning, mouth rinsing with 20ml Cetylpyridium Chloride daily for 24 weeks

干预措施: Cetylpyridium chloride (Other)

结局指标

主要结局

Reduction of oral malodour below threshold

时间窗: 1, 12, 24 weeks

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Leeann Donnelly

Assistant Professor, Dept. Oral Biological and Medical Sciences

University of British Columbia

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