Treatment Protocol for Recurrent Cases of Bacterial Posterior Blepharitis

Not Applicable

Recruiting

• Conditions: posterior blepharitis; blepharitis

• Registration Number: JPRN-jRCT1071230068
• Lead Sponsor: ejima Ryohei

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-09-29
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1) Patients 16 years of age or older with posterior blepharitis (with or without concurrent anterior blepharitis)
2) Patients with a history of bacterial posterior blepharitis in the same eye previously treated with 1% azithromycin ophthalmic solution
3) Patients with a total score of 4 or more of signs (eyelid redness eyelid margin redness, eyelash discharge, and conjunctival hyperemia) and symptoms (foreign body sensation, lacrimation) and a score of 1 or more of eyelid redness eyelid margin redness, and a score of 1 or more of symptoms.
4) Patients who are able to administer ophthalmoplegia appropriately.
5) Patients who understand the contents of the consent document and are able to give written consent
6) Patients who are able to come to the hospital on the day of observation as instructed by the investigator.

Exclusion Criteria

1) Patients presenting with anterior blepharitis only
2) Patients with eyelid diseases other than blepharitis (e.g., entropion, eyelid tumor)
3) Patients with bacterial, fungal, viral, allergic, or other inflammatory diseases of the external eye (e.g., conjunctivitis, keratitis) other than blepharitis
4) Patients with severe ocular surface disease
5) Patients who have received topical or systemic administration of antibacterial agents (except 1% azithromycin ophthalmic solution), steroids, or immunosuppressive agents within the past 2 weeks
6) Patients who have used 1% azithromycin ophthalmic solution within 3 weeks
7) Patients deemed inappropriate for inclusion in this study by the principal investigator (investigator, etc.)
8) Other patients who the principal investigator (investigator, etc.) determines to be inappropriate for the safe conduct of this study.

Study & Design

• Study Type: Observational
• Study Design: Not specified