Concentrated Platelet Rich Fibrin (C-PRF) as Adjunct to Non-surgical Periodontal Therapy- a Split Mouth Randomized Clinical Trail
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 48
- 试验地点
- 2
- 主要终点
- Probing pocket Depth
研究概览
简要总结
The current study is a prospective randomised split mouth study to evaluate the effect of concentrated Platelet Rich Fibrin as an adjunct to the scaling and root planing
详细描述
Twelve healthy individuals satisfying the inclusion and exclusion criteria were recruited for the study. A detailed, thorough medical and dental history was obtained and each patient was subjected to comprehensive clinical and radiological examination. All patients were informed about the nature of the study, procedure involved, potential benefits and risks associated with procedure and written informed consent were obtained from all patients.
All the patients underwent scaling and root planing. As it is split mouth study design the test site is treated with Concentrated platelet rich fibrin( C-PRF) and the contralateral site is not treated with C-PRF. Periodotal pack was placed and patient was recalled after 6 weeks for the follow up.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patient age ranging from 18-45 years
- •Contralateral sites with probing depth 5mm-7mm associated with premolar and molar teeth with no furcation involvement
- •No systemic disease
- •Not under any medication which effect the outcome of periodontal therapy
排除标准
- •History of any periodontal therapy within past 6 months
- •Pregnant and lactating mothers
- •Smokers smoking >10 cigarettes per day
- •Patients with blood disorders or platelet count less than 50000 cells/ µL
- •Patients with known systemic disease
- •Non-compliant patients
结局指标
主要结局
Probing pocket Depth
时间窗: 6 weeks
measured using a UNC-15 probe (university of North Carolina-15 periodontal probe- Hu-Friedy, Chicago, IL, USA)
Relative attachment level
时间窗: 6 weeks
measured by placing the acrylic stent on the selected teeth using UNC-15 probe (university of North Carolina-15 periodontal probe- Hu-Friedy, Chicago, IL, USA)
次要结局
未报告次要终点