Efficacy of Chest Physical Therapy on Arterial Blood Gases for Neonates Post Hypoxic Ischemic Encephalopathy in Neonatal Intensive Care Unit: A Clinical Trial Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 50
- 主要终点
- Timing of Arterial blood gases improvement
研究概览
简要总结
Hypoxic-ischemic encephalopathy (HIE) is a dangerous illness that happens when a newborn's brain does not receive adequate oxygen and blood flow, which can result in serious effects such as cerebral palsy and epilepsy. Infant diagnosed with HIE required ventilator support and subsequently developed pneumonia. They experienced respiratory problems and feeding challenges. Chest Physical Therapy is the best modalities to clear chest and improve ventilation.
详细描述
The purpose of this study to investigate the effect of chest physical therapy on Arterial Blood Gases for neonates post hypoxic ischemic encephalopathy (HIE) in Neonatal intensive care unit.
Methods: Fifty neonates from both sexes, age from birth to 10 days, post HIE with chest problems were selected from neonatal intensive care unit (NICU) at Minia University hospital, Egypt. They were divided into two equal groups, control group (CG) received traditional medical treatment according to American Academy of Pediatrics (AAP) recommendations and study group (SG) received traditional medical treatment plus Chest Physical Therapy (CPT) modalities in the form of postural drainage, percussion and vibration. The sessions will apply once daily for 6 days/week, each session is about 30 minutes, according to the neonate tolerance till complete clinical cure and discharge from NICU.
the outcome will measure by Timing of Arterial blood gases improvement, Duration required for clinical improvement, Duration of Mechanical ventilation, Duration of Hospitalization.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 1 Day 至 10 Days（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Neonates with chest problems post Hypoxic-ischemic encephalopathy
排除标准
- •Neonates with chest problems due to other Causes except post Hypoxic-ischemic encephalopathy.
- •unstable medical status
- •Neonates with Post-operative s' respiratory problems due to any reasons.
研究组 & 干预措施
Chest physical Therapy group
Study group
干预措施: Chest Physical Therapy (CPT) modalities , Medical Treatment (Other)
Medical treatment group
Control group
干预措施: Chest Physical Therapy (CPT) modalities , Medical Treatment (Other)
结局指标
主要结局
Timing of Arterial blood gases improvement
时间窗: 3-14 days
Time needed to improve Arterial blood gases due to CPT
Timing required for clinical improvement
时间窗: 3-14 days
Time needed to improve clinical signs due to CPT
Timing needed for Mechanical Ventilation
时间窗: 3-7 days
Time needed to Mechanical Ventilation support.
Hospitalization time
时间窗: 5-21 days
All staying duration need for the neonates from admission till discharge from the hospital.
次要结局
未报告次要终点
研究者
Elsayed Mehrem
Principal Investigator
Cairo University