Does high intensity intermittent exercise promote health and wellbeing in overweight and obese men?
Completed
- Conditions
- ObesityNutritional, Metabolic, Endocrine
- Registration Number
- ISRCTN90672085
- Lead Sponsor
- oughborough University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Male
- Target Recruitment
- 16
Inclusion Criteria
1. BMI = 27 kg·m-2
2. Reported taking part in any form of exercise less than 2 times per week
3. Otherwise healthy
4. Male
Exclusion Criteria
1. Smokers
2. Previously diagnosed with impaired fasting glucose or diabetes
3. BMI = 40 kg.m-2
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Fasting glucose is measured via an oral glucose tolerance test (OGTT) which will be performed one week prior to intervention and 72 hours immediately post the last exercise session in week two.
- Secondary Outcome Measures
Name Time Method Inflammatory profile is assessed at baseline, 1 week prior to intervention and once again 72 hours post-the final exercise bout. Inflammatory profile is assessed by measuring:<br>1. Adiponectin, MCP-1 and CRP using commercial sandwich enzyme linked immunosorbent assays (ELISAs)<br>2. CRP and TNF-avia using high sensitivity ELISAs (R & D systems, Minneapolis, MN, USA)<br>3. Plasma IL-6 and sIL-6R via ‘in-house’ ELISAs