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临床试验/NCT05010941
NCT05010941已完成不适用

Performance of the Hypotension Prediction Index in Living Donor Liver Transplantation

Seoul National University Hospital1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2021年8月13日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
20
试验地点
1
主要终点
Prediction of Hypotension 5 Minutes Before the Event

研究概览

简要总结

The Hypotension Prediction Index via the Edwards Hemosphere advanced monitoring system is monitored in living donor liver transplantation recipients. The Hypotension Prediction Index is analyzed to verify the performance in predicting hypotensive events.

详细描述

Hypotensive events during surgery and anesthesia occur frequently and are associated with complications such as myocardial infarction, acute kidney injury, and increase in mortality. Therefore predicting and preventing hypotension can lead to better outcomes.

The Hypotension Prediction Index is monitored with the Edwards Hemosphere advanced monitoring system in living donor liver transplantation recipients via the radial artery. The monitor is blinded so that the anesthesiologist cannot see the index, and the anesthesiologist manages the blood pressure according to the institution's anesthetic protocol for liver transplantation. After the surgery is done, the Hypotension Prediction Index is analyzed to see how well the index predicted actual hypotension that occured during the liver transplantation surgery. Receiver operating characteristic curves are drawn to show the performance of the Hypotension Prediction Index in liver transplantation.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
20 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients scheduled for living donor liver transplantation aged 20 years and older
  • Patients who understand the trial and have given informed consent

排除标准

  • Patients with arrhythmia or pacemaker

结局指标

主要结局

Prediction of Hypotension 5 Minutes Before the Event

时间窗: During the surgery

Receiver operating characteristic curve for the Hypotension Prediction Index, Comparison of the hypotensive event and the Hypotension Prediction Index 5 minutes before the event

次要结局

  • Prediction of Hypotension 15 Minutes Before the Event(During the surgery)
  • Prediction of Hypotension 10 Minutes Before the Event(During the surgery)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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