Observational study to predict the change in perfusion index during Endotracheal intubation and extubation under General Anaesthesia.

Not yet recruiting

• Conditions: Measurement and Monitoring,

• Registration Number: CTRI/2025/06/088514
• Lead Sponsor: Gagan Virk

Brief Summary

This is a prospective observational study to evaluate and assess that ,Perfusion Index is used to detect hemodynamic stress response at different time intervals (1,2,3,4,5,10 min post intubation, start and end of Neuromuscular block, pre extubation and post extubation at 1,2,3,4,5 min). sample size of 50 participants undergoing general anesthesia is calculated with Inclusion and Exclusion criteria. Baseline parameters recorded , then parameters recorded during Intubation , at the time of reversal and extubation.All the data will be entered on to a micro soft excel spread sheet and analysed by using  appropriate tests .

Detailed Description

Not available

Study Timeline

• Study Start: 2025-06-21
• Last Update Posted: 2025-10-06

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Patients willing to give consent BMI less than 30 ASA 1 and 2 Patients undergoing to elective surgery under general anesthesia and perform oral endotracheal intubation.

Exclusion Criteria

Patient with a history of sore throat or upper respiratory tract infection Hemodynamically unstable patients Pregnant women Patients with a history of cardio-pulmonary disease, liver, or renal disorders and any chronic disease and history of drug allergy Patients with anticipated and unanticipated difficult airway.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To observe and compare the PI changes from baseline PI at different time intervals 1,2,3,4,5,10 min post intubation, start and end of Neuromuscular block, pre extubation and post extubation at 1,2,3,4,5 min.	1,2,3,4,5,10 min post intubation and extubation

Secondary Outcome Measures

Name	Time	Method
To assess & compare changes in the Rate pressure product (HR × SBP) at different time intervals from baseline rate pressure product	1,2,3,4,5,10 min
To observe & compare changes in hemodynamic parameters (HR, SBP,DBP, & MAP) from baseline hemodynamic parameters at different time intervals & any correlation with PI.	1,2,3,4,5,10 min
To assess & compare of significant HR SBP DBP MBP & PI (increase HR more than 10 BPM, increase SBP & DBP more than 15mmhg, PI decrease in more than 10 percent) at different time intervals from baseline values of these parameters	1,2,3,4,5,10 min

Trial Locations

Locations (1)

Jhalawar medical college and hospital; 🇮🇳 Jhalawar, RAJASTHAN, India

Jhalawar medical college and hospital

🇮🇳Jhalawar, RAJASTHAN, India

Dr Gagan virk

Principal investigator

8126295777

virkgagan594@gmail.com