A study to evaluate the effectiveness of perfusion index as a predictor of haemodynamic response at the time of endotracheal Intubation and extubation in elective surgery under General Anaesthesia : A prospective observational study.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- To observe and compare the PI changes from baseline PI at different time intervals 1,2,3,4,5,10 min post intubation, start and end of Neuromuscular block, pre extubation and post extubation at 1,2,3,4,5 min.
研究概览
简要总结
This is a prospective observational study to evaluate and assess that ,Perfusion Index is used to detect hemodynamic stress response at different time intervals (1,2,3,4,5,10 min post intubation, start and end of Neuromuscular block, pre extubation and post extubation at 1,2,3,4,5 min). sample size of 50 participants undergoing general anesthesia is calculated with Inclusion and Exclusion criteria. Baseline parameters recorded , then parameters recorded during Intubation , at the time of reversal and extubation.All the data will be entered on to a micro soft excel spread sheet and analysed by using appropriate tests .
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients willing to give consent BMI less than 30 ASA 1 and 2 Patients undergoing to elective surgery under general anesthesia and perform oral endotracheal intubation.
排除标准
- •Patient with a history of sore throat or upper respiratory tract infection Hemodynamically unstable patients Pregnant women Patients with a history of cardio-pulmonary disease, liver, or renal disorders and any chronic disease and history of drug allergy Patients with anticipated and unanticipated difficult airway.
结局指标
主要结局
To observe and compare the PI changes from baseline PI at different time intervals 1,2,3,4,5,10 min post intubation, start and end of Neuromuscular block, pre extubation and post extubation at 1,2,3,4,5 min.
时间窗: 1,2,3,4,5,10 min post intubation and extubation
次要结局
- To assess & compare changes in the Rate pressure product (HR × SBP) at different time intervals from baseline rate pressure product(1,2,3,4,5,10 min)
- To observe & compare changes in hemodynamic parameters (HR, SBP,DBP, & MAP) from baseline hemodynamic parameters at different time intervals & any correlation with PI.(1,2,3,4,5,10 min)
- To assess & compare of significant HR SBP DBP MBP & PI (increase HR more than 10 BPM, increase SBP & DBP more than 15mmhg, PI decrease in more than 10 percent) at different time intervals from baseline values of these parameters(1,2,3,4,5,10 min)