Neuro-Orthopaedic Disorders During Aging in Patients With Neuromotor Disability

Recruiting

• Conditions: Disability or Chronic Disease Leading to Disablement
• Interventions: Other: standard of care for patients with neuromotor disability

• Registration Number: NCT05294029
• Lead Sponsor: Institut de Sante Parasport Connecte Synergies

Brief Summary

People with neuromotor disability (i.e. following an inborn or acquired spinal cord, cerebral or peripheral neurological lesion) are at risk of worsening their neuro-orthopaedic disorders during aging, including fracture risk. Nevertheless, at the present time, the natural evolution of their neuro-orthopedic disorders and the long-term functional impact of their medical and surgical treatments is unknown.

The aim of this study is to describe neuro-orthopedic disorders during aging of patients with neuromotor disability, their functional repercussions, their comorbidities and the therapeutic strategies used.

Detailed Description

This is an ambispective, monocentric, cohort study of subjects with neuromotor disability followed in a Physical Medicine and Rehabilitation Department.

All consecutive eligible inpatient and outpatient subjects treated in the Neuro Orthopaedic Unit (UPOH) of the Physical Medicine and Rehabilitation Department of our university hospital will be included.

Data will be collected from the patients' medical records, in particular data related to their clinical, radiological, biological and physiological examinations.

Study Timeline

• Study First Submitted: 2022-01-05
• Study First Submitted QC: 2022-03-15
• Study First Posted: 2022-03-24
• Study Start: 2022-05-01
• Status Verified: 2022-12
• Last Update Submitted: 2022-12-21
• Last Update Posted: 2022-12-23
• Primary Completion: 2032-02-01
• Study Completion: 2034-02-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 2000

Inclusion Criteria

• Patients >= 18 years old ;
• Treated in the Neuro Orthopaedic Unit (UPOH) of the Physical Medicine and Rehabilitation Department of our university hospital ;
• Having a neuromotor disability ;
• No opposition to be enrolled in the study from the patient, or from a legally authorized close relative if the patient's state of health does not allow it ;
• Affiliation to a social security scheme.

Exclusion Criteria

• Under court protection.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
All subjects with neuromotor disability	standard of care for patients with neuromotor disability	-

Primary Outcome Measures

Name	Time	Method
Evolution of mobility during aging	Through study completion, an average of 1 year	Walking range

Secondary Outcome Measures

Name	Time	Method
Changes of devices (orthoses and prostheses) and technical aids used during aging	Through study completion, an average of 1 year	Number and description of devices (orthoses and prostheses) and technical aids
Changes of physical activity, as well as barriers and facilitators to physical activity, during aging	Through study completion, an average of 1 year	Questionnaires assessing physical activity levels (ex: PASPID) and barriers and facilitators to physical activity (ex: BPAQ)
Evolution of comorbidities during aging	Through study completion, an average of 1 year	Prevalence of comorbidities (e.g. obesity, diabetes, hypertension, sleep apnea, ...)
Medication	Through study completion, an average of 1 year	Medication list
Characteristics of infiltrative procedures and surgeries	Through study completion, an average of 1 year	Number and description of infiltrative procedures and surgeries
Prevalence of falls and fractures	Through study completion, an average of 1 year	Number and description of falls and fractures
Prevalence of pressure sores	Through study completion, an average of 1 year	Number and description of pressure sores

Trial Locations

Locations (1)

Department of Physical Medicine and Rehabilitation, Raymond Poincaré Hospital, AP-HP; 🇫🇷 Garches, France