Effect of Prone Positioning in Patients With COVID-19

Not Applicable

Completed

• Conditions: Covid19

• Registration Number: NCT04710771
• Lead Sponsor: Sialkott College of Physical Therapy

Brief Summary

COVID-19 is affecting the people around the world and the infected individuals' may either stay asymptomatic or present to hospitals with severe distress and life threatening symptoms. The objective of the study is to investigate role of Prone positioning and alternate nostril breathing in patients with Covid-19.

Detailed Description

In this quasi experimental study, 30 patients aged 40-80 years of either gender with a confirmed diagnosis of COVID-19 receiving supplemental oxygen were recruited from DHQ Hospital Faisalabad. patients were grouped into two A \& B. We collected baseline data on demographics and anthropometrics. After baseline data collection, all the patients were helped into the prone position, which was maintained for a minimum duration of three hours. After that patients in group B performed alternate nostril breathing for 10 minutes with help of physiotherapist. Clinical data were re-collected on 3rd day of intervention one hour after returning to the supine position in group A and after alternate nostril breathing in group B. The main study outcome was the variation in oxygenation (partial pressure of oxygen \[PaO2\]/ fractional concentration of oxygen in inspired air \[FiO2\]) between baseline and resupination, and General psychological state through GAD-7 General anxiety disorder questionnaire.

Study Timeline

• Study Start: 2020-11-23
• Study First Submitted: 2021-01-09
• Study First Submitted QC: 2021-01-13
• Primary Completion: 2021-01-15
• Study First Posted: 2021-01-15
• Study Completion: 2021-01-29
• Status Verified: 2025-05
• Last Update Submitted: 2025-05-12
• Last Update Posted: 2025-05-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Age: 40-80 Gender: Both GCS score:15

Exclusion Criteria

• COPD Intubated ARDS Smoker Neurological Disorder

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
FiO2	Change in score before the intervention on 1st day of intervention and on 3rd day one hour after the intervention.	Fractional concentration of oxygen in inspired air \[FiO2\])
PaO2	Change in score before the intervention on 1st day of intervention and on 3rd day one hour after the intervention.	partial pressure of oxygen.
General Anxiety Disorder-7 Score	Change in score before the intervention on 1st day of intervention and on 3rd day one hour after the intervention.	general anxiety disorder-7 score ranges from 0-21, out of which 0-4 means minimal anxiety, 5-9 stands for mild anxiety, 10-14 for moderate and 15-21 for severe anxiety.

Trial Locations

Locations (1)

DHQ Hospital; 🇵🇰 Faisalabad, Punjab, Pakistan