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Clinical Trials/NCT04851262
NCT04851262CompletedNot Applicable

Home-based Progressive Resistance Exercise to Enhance Physical Performance of Older Adults With Possible Sarcopenia

The University of Hong Kong1 site in 1 country42 target enrollmentStarted: January 1, 2021Last updated:
Conditions
Interventions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
42
Locations
1
Primary Endpoint
Change in lower-limb muscle strength at 12 weeks from baseline

Study Overview

Brief Summary

The overall aim of the proposed project is to improve muscle strength in older adults with possible sarcopenia by promoting home-based progressive resistance exercise. The target population for health talks is community-dwelling older adults. A Three monthly home-visits and weekly phone calls will be made. A waitlist randomised controlled trial will be conducted to evaluate effectiveness, and qualitative feedback will be collected from participants. A pilot study will be conducted first.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Prevention
Masking
Single (Outcomes Assessor)

Eligibility Criteria

Ages
65 Years to 89 Years (Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •The inclusion criteria are:
  • •Aged 65-89;
  • •Possible sarcopenia (defined by AWGS 2019);
  • •No cognitive impairment (Abbreviated Mental Test score ≥8); and
  • •No communication problems.

Exclusion Criteria

  • •having engaged in a structured exercise programme in the past 6 months or planning to do so within the intervention period;
  • •mobility-limiting injury of the hands or lower limbs, surgery or hospitalisation within the intervention period;
  • •contraindications such as musculoskeletal/cardiorespiratory disorders, or any advanced diseases that inhibit them from exercising.

Arms & Interventions

Intervention

Experimental

The intervention is a 12-week home-based resistance training programme with phased progression. The intervention will have three phases: (i) an initial phase focused on training the target muscle(s)/movements with minimal or no external weight; (ii) an intermediate phase targeting muscle strength with increased practice resistance; and (iii) an advanced phase targeting the further enhancement of muscle strength by challenging multiple muscle groups. Each phase will involve exercises targeting the trunk, back, hip, upper-limb and lower-limb muscles.

Intervention: Exercise (Behavioral)

Waitlist control

Other

The waitlist control participants will start the intervention 12 weeks after the baseline assessment.

Intervention: Exercise (Behavioral)

Outcomes

Primary Outcomes

Change in lower-limb muscle strength at 12 weeks from baseline

Time Frame: 12 weeks after baseline

Measured by Short Physical Performance Battery (SPPB), higher score indicates better performance

Secondary Outcomes

  • Change in lower-limb muscle strength at 24 weeks from baseline(24 weeks after baseline)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Dr. Pui-Hing Chau

Associate Professor

The University of Hong Kong

Study Sites (1)

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