A double-blind randomized placebo controlled Clinical study to evaluate the effectiveness and safety of Formulation HB01 for instant relief from heartburn.

Heartburn is a burning pain in your chest, just behind your breastbone. The pain is often worse after eating, in the evening, or when lying down or bending over. Occasional heartburn is common and no cause for alarm. Most people can manage the discomfort of heartburn on their own with lifestyle changes and nonprescription medications. Heartburn that is more frequent or interferes with your daily routine may be a symptom of a more serious condition that requires medical care. The majority of medical professionals concur that lower esophageal dysfunction is caused by the reflux of stomach or duodenal contents into the oesophagus. It could be regarded as a functional disorder if there isn’t a visible hiatus hernia or esophagitis. Globus has also been described as being indicative of an esophageal functioning abnormality. When unrelated to dyspepsia, this sensation of having a "lump in the throat" is thought to be caused by the upper esophageal sphincter malfunctioning. Additionally, holding back tears is thought to be a physical example of suppressed emotion. Although a lot of money and time is spent treating the symptoms of these two esophageal disorders, little is known about their prevalence, how they relate to one another, or how they differ from other functional gastrointestinal disorders

Screeningand Assigning: Day 0

SubjectAssessment: Day 1

Follow-up:Day 2 for any adverse event