Effect of Pioglitazone on kidney transplantation in diabetic patients

Not Applicable

• Conditions: Condition 1: Diabetis. Condition 2: Transplanted kidney.; Insulin-dependent diabetes mellitus; transplanted kidney

• Registration Number: IRCT2012121811807N1
• Lead Sponsor: Deputy of Research and Technology, Shahid beheshti pharmacy faculty

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1-diabetis mellitus. 2- stable renal function at the initiation of study or 1 month after transplantation. 3- using insulin before study
Exclusion criteria:
1- acute febrile episodes.
2- GFR less than 30 ml/dl before the study.
3-hepatitis B , C.
4- CHF (New York Heart Association II-IV)
5-pregnancy.
6-receiving pulse corticostroids.
7-Acute rejection at 2 week before of study starting.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Malondialdehyd plasma level. Timepoint: at the begining and end. Method of measurement: Pg/mL.;Total protein carbonyls plasma level. Timepoint: at the begining and end. Method of measurement: Pg/mL kit.;IL-18 plasma level. Timepoint: at the begining and end. Method of measurement: (Pg/mL) kit.;Fast blood glucose. Timepoint: monthly. Method of measurement: kit ( mg/dL).;ESR level. Timepoint: monthly. Method of measurement: (Pg/mL) kit.;CRP plasma level. Timepoint: monthly. Method of measurement: (ng/mL) kit.;HbA1C level. Timepoint: monthly. Method of measurement: (mIU/mL) kit.