Cardiac and intramuscular adaptations following short-term exercise prehabilitation in unfit patients scheduled to undergo hepatic or pancreatic surgery - CIRCULATE

niversitair Medisch Centrum Groningen0 个研究点目标入组 12 人开始时间: 待定最近更新: 2024年7月15日

适应症

试验速览

暂无简介。

•- VO2 at the ventilatory anaerobic threshold (VAT) <=13 ml/kg/min and/or VO2peak
•<=18 ml/kg/min, as determined during the baseline CPET;
•- More than 18 years of age;
•- Scheduled for elective liver- or pancreatic resection at the UMCG;
•- Willing to participate in the home-based bimodal prehabilitation program;
•- Has given consent to participate in the study

•- Patients requiring acute (emergency) surgery;
•- Patients not capable of cycling on a cycle ergometer;
•- Patients with contraindications to physical exercise training;
•- Patients receiving neoadjuvant chemotherapy
•- Contraindications for exCMR (e.g., claustrophobia, implanted cardiac devices)
•- Atrial fibrillation or other significant arrhythmia during the exCMR and
•31P-MRS procedures;
•- Body weight >140 kg;
•- Body length > 190cm
•- History of myocardial infarction, percutaneous coronary intervention or
•coronary artery bypass graft <3 months or untreated severe obstructive coronary
•artery stenosis;
•- More than moderate left-sided valve disease;
•- Complex congenital heart disease.

发起方