NL-OMON53378
Recruiting
Not Applicable
Cardiac and intramuscular adaptations following short-term exercise prehabilitation in unfit patients scheduled to undergo hepatic or pancreatic surgery - CIRCULATE
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- hepatopancreatobiliary malignancies
- Sponsor
- niversitair Medisch Centrum Groningen
- Enrollment
- 12
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- VO2 at the ventilatory anaerobic threshold (VAT) \<\=13 ml/kg/min and/or VO2peak
- •\<\=18 ml/kg/min, as determined during the baseline CPET;
- •\- More than 18 years of age;
- •\- Scheduled for elective liver\- or pancreatic resection at the UMCG;
- •\- Willing to participate in the home\-based bimodal prehabilitation program;
- •\- Has given consent to participate in the study
Exclusion Criteria
- •\- Patients requiring acute (emergency) surgery;
- •\- Patients not capable of cycling on a cycle ergometer;
- •\- Patients with contraindications to physical exercise training;
- •\- Patients receiving neoadjuvant chemotherapy
- •\- Contraindications for exCMR (e.g., claustrophobia, implanted cardiac devices)
- •\- Atrial fibrillation or other significant arrhythmia during the exCMR and
- •31P\-MRS procedures;
- •\- Body weight \>140 kg;
- •\- Body length \> 190cm
- •\- History of myocardial infarction, percutaneous coronary intervention or
Outcomes
Primary Outcomes
Not specified
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