Role of the intestine on osteoarthritis of the hand and the effect of Sustained Release Calcium Butyrate. - Intestine and osteoarthritis

BirrBeheerBV0 个研究点目标入组 33 人开始时间: 2021年12月3日最近更新: 2022年2月7日

适应症

试验速览

暂无简介。

•-Age = 50 year and = 75 years,
•-Osteoarthritis of the hand according to the 1990 ACR diagnostic criteria for hand OA (Altman 1990) in both hands operationalized as:
•Hand pain, aching, or stifness and 3 or 4 of the following:
•Hard tissue enlargement of 2 or more of 10 selected joints
•Hard tissue enlargement of 2 or more DIP joints
•Fewer than 3 swollen MCP joints
•Deformity of at least 1 of 10 selected joints.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 33
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 33

•-Recent use of antibiotics (last three months)
•-Previous surgery of one of the hands
•-Recent cerebro- or cardiovascular incident (past 6 months)
•-Other chronic inflammatory disease
•-Other musculoskeletal diseases than OA with possible hand localisation
•-Cognitive deficits affecting the scoring process
•-Received intramuscular of intra-articular corticosteroid injections in the previous 4 weeks
•-Fibromyalgia according to the 2010 ACR diagnostic criteria for fibromyalgia (Wolfe 2011)
•-Any other syndrome(s) or condition(s) that could interfere with the assessment of pain
•-Severe current psychiatric disorders assessed by physician
•-Self-reported consumption of alcoholic drinks, > 2 units per day

发起方

BirrBeheerBV