Evaluation of CPD MNV as an Aid in the Diagnosis and Risk Assessment of Sepsis (Protocol # Sepsis 1-14)

Completed

• Conditions: Sepsis, Severe Sepsis and Septic Shock

• Registration Number: NCT02232750
• Lead Sponsor: Ohio State University

Brief Summary

The investigators hypothesize that CPD parameters will provide improved prediction of sepsis compared to currently employed laboratory parameters. These studies hold the potential to shape practitioner guidelines and improve the timeliness and accuracy with which patients with sepsis are treated today.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-07-14
• Study First Submitted: 2014-08-26
• Study First Submitted QC: 2014-09-02
• Study First Posted: 2014-09-05
• Primary Completion: 2015-08-15
• Study Completion: 2015-08-15
• Status Verified: 2021-11
• Last Update Submitted: 2021-11-01
• Last Update Posted: 2021-11-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1320

Inclusion Criteria

• Adult (≥18 to 90 years)
• Patients presenting to the Emergency Department
• CBC (Complete Blood Count) with differential testing performed and CPD data retrieved

Exclusion Criteria

• Previously enrolled in this study

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
We are measuring CBC (complete blood count) and MNV (Mean Neutrophil Volume)	approximately 10 months	Evaluate the clinical utility of CPD MNV as an aid in the diagnosis and risk assessment of Emergency Department patients for progression to sepsis, severe sepsis and septic shock.

Trial Locations

Locations (1)

Wexner Medical Center at The Ohio State University; 🇺🇸 Columbus, Ohio, United States