Analgesic Efficacy of Adding Dexmedetomidine VS Magnesium Sulphate as Adjuvants With Bupivacaine in Ultrasound-guided Erector Spinae Plane Block for Post Thoracotomy Pain
Overview
- Phase
- Not Applicable
- Intervention
- Bupivacaine
- Conditions
- Analgesia
- Sponsor
- National Cancer Institute, Egypt
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- Total postoperative morphine consumption
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
Postoperative pain management is considered an integral part of perioperative care in patients undergoing thoracotomy. In order to reduce these complications, multiple regional techniques have been developed for thoracotomy including Intercostal nerve block, Erectospinae plane block and serratus block. Multiple adjuvants have been used in regional analgesia including adrenaline,clonidine,magnesium sulphate,dexmedatomidine and opoids.
Investigators
Walaa Youssef Elsabeeny
Assistant professor of Anesthesia and Pain management
National Cancer Institute, Egypt
Eligibility Criteria
Inclusion Criteria
- •Age from 18 to 65 years.
- •Male and female sexes.
- •ASA I-II.,III
- •Cancer patients undergoing thoracotomy incisions
- •Body mass index (BMI) from 18.5 to 30 kg/m2
Exclusion Criteria
- •Patient refusal
- •Known allergy to any of the used drugs
- •Low platelet count, any coagulation defect
Arms & Interventions
Erector spinae plane block with 0.25% bupivacaine
Patients will receive ultrasound guided ESPB with 0.25% bupivacaine
Intervention: Bupivacaine
Erector spinae plane block with 0.25% bupivacaine and Magnesium
Patients will receive ultrasound guided ESPB with 0.25% bupivacaine and magnesium
Intervention: Bupivacaine + Magnesium
Erector spinae plane block with 0.25% bupivacaine and Dexmedetomidine
Patients will receive ultrasound guided ESPB with 0.25% bupivacaine and dexmedetomidine
Intervention: Bupivacaine + Dexmedetomidine
Outcomes
Primary Outcomes
Total postoperative morphine consumption
Time Frame: First 24 hours postoperatively
Total dose of morphine needed postoperatively in the first 24 h
Secondary Outcomes
- Time to first postoperative rescue analgesia.(First 24 hours postoperatively)