NCT01374347已完成不适用
Brain SPECT Perfusion Imaging Following Cialis (Tadalafil ) Administration in Patients With Vascular Risk Factors
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
研究概览
简要总结
The study will be an open label one and will include 30 patients who underwent ischemic stroke 3 month to 3 years prior to the study. All patients will undergone a baseline brain SPECT perfusion study. 15 patients will take one dose of 20 mg cialis, and will have a second brain SPECT 24 hours after cialis administration. 15 other patients (age and risk factor matched) will be prescribed 5 mg of cialis once daily for 7 days, and a second SPECT study will be performed 24 hours after the last dose.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 35 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Male and female patients in the age range of 35-75 years.
排除标准
- •known allergic reaction to TF
- •Medical contraindication to use TF
- •Hemorrhagic stroke including intracerebral hemorrhage and subarachnoid hemorrhage
- •Acute stroke or cardiac ischemic event up to 3 month prior to study.
- •Other neurological brain diseases including degenerative diseases, multiple sclerosis, brain tumors, post severe brain injury (TBI) and migraine headache.
- •Sensory aphasia.
- •Cognitive impairment with disability to sign a consent form.Patients' Assessment
研究者
Mordechai Lorberboym Prof
PI
Wolfson Medical Center
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