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Clinical Trials/NCT05910320
NCT05910320
Terminated
Not Applicable

Evaluation of an Investigational Wearable Vital Signs Monitoring Device in Healthy Infants

Johns Hopkins University1 site in 1 country3 target enrollmentMay 23, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Congenital Heart Disease in Children
Sponsor
Johns Hopkins University
Enrollment
3
Locations
1
Primary Endpoint
Signal morphology of wearable monitoring device
Status
Terminated
Last Updated
9 months ago

Overview

Brief Summary

The primary objective of this study is to evaluate the feasibility of the use of an investigational wearable vital sign monitoring device in infants.

Detailed Description

Vital sign monitoring of infants outside of a traditional healthcare setting has already been shown to significantly decrease mortality for children with single ventricle congenital heart disease (1V CHD), a fragile group of patients with congenital heart disease (CHD). Therefore, there is a critical need to develop an accurate, at-home vital sign monitoring system for infants to expand the benefits of remote monitoring to further patient populations. The investigators believe that allowing for continuous monitoring at a clinical standard with interpretations and alerts built into the technology will result in an even greater decline in mortality for infants with 1V CHD, improved clinical outcomes for all infants with CHD, and increased well-being for healthy infants. To achieve this goal, the investigators are developing a health monitoring system that collects numerical data and physiological waveforms describing heart rate (HR), respiratory rate (RR), pulse oximetry (SpO2), regional oxygen saturation, temperature, and infant motion.

Registry
clinicaltrials.gov
Start Date
May 23, 2023
End Date
June 24, 2025
Last Updated
9 months ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patient admitted to either the newborn nursery, pediatric cardiac intensive care unit (PCICU), or pediatric care unit (PCU)
  • Parent provided written informed consent

Exclusion Criteria

  • Foster or ward of the state

Outcomes

Primary Outcomes

Signal morphology of wearable monitoring device

Time Frame: From device placement to removal, up to 1 hour

Feasibility of a wearable monitoring device as determined by signal morphology of wearable monitoring device

Signal-to-noise ratio of wearable monitoring device

Time Frame: From device placement to removal, up to 1 hour

Feasibility of a wearable monitoring device as determined by signal-to-noise ratio

Signal-to-noise ratio of reusable electrodes

Time Frame: From electrode placement to removal, up to 15 minutes

Feasibility of reusable electrodes as determined by the signal-to-noise ratio

Percent error of wearable monitoring device compared to clinical bedside monitors

Time Frame: From device placement to removal, up to 1 hour

Feasibility of a wearable monitoring device as determined by percent error compared to clinical bedside monitors

Study Sites (1)

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