The Effect of Coffee Consumption and Body Weight on the Serum Levels of Leptin, Folic Acid, and Vitamin B12 in Young Males: A Cross-Sectional Study
试验速览
- 阶段
- 不适用
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- leptin
研究概览
简要总结
The effect of coffee and body weight during the last 3 months on the level of leptin, folic acid, and vitamin B12
详细描述
Coffee consumption has been associated with several risk factors leading to cardiovascular diseases (CVDs), including hyperhomocysteinemia and hyperlipidemia. Frequent coffee consumption has beneficial effects in reducing the risk of diabetes mellitus (DM) type 2, obesity, liver disease, CVDs, some types of cancer, Parkinson's disease, and Alzheimer's disease. Controversies concerning coffee consumption benefits and risks in regards for CVDs were mentioned in many studies. Folic acid and vitamin B12 are necessary vitamins in homocysteine metabolism which is a risk factor for atherosclerosis. Leptin, is a hormone linked to obesity and it could be related to atherosclerosis.
The combined effect of coffee consumption and body weight on the levels of leptin, folic aid, and vitamin B12 is not well studied. In our study, we will study the effect of coffee consumption in males with different body mass indices to see the effect of several important parameters such as leptin, Folic acid, and vitamin B12.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 26 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •ASU student,
- •do not have any acute or chronic medical conditions.
排除标准
- •students who used any medications for either an acute and/or a chronic condition during the past 3 months prior to the study entry.
结局指标
主要结局
leptin
时间窗: Baseline
Plasma Concentration of leptin in ng /ml
folic acid
时间窗: Baseline
Plasma Concentration of folic acid in ng /ml
Vitamin B12
时间窗: Baseline
Plasma Concentration of Vitamin B12 in pg /ml
次要结局
- fasting blood glucose(Baseline)
- lipid profile(Baseline)