EUCTR2014-000975-21-ES
Active, not recruiting
Phase 1
A phase IV study to evaluate the effectiveness of aflibercept in naive patients with macular edema secondary to Central Retinal Vein Occlusion (CRVO) on an individualized Treat and Extend regimen. NEUTON study. - NEUTO
Fundación Retinaplus +0 sitesJune 9, 2014
ConditionsMacular edema secondary to central retinal vein occlusion.Therapeutic area: Diseases [C] - Eye Diseases [C11]
DrugsEylea
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Macular edema secondary to central retinal vein occlusion.
- Sponsor
- Fundación Retinaplus +
- Status
- Active, not recruiting
- Last Updated
- 9 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- Patient ? 50 years old
- •\- Patient with newly diagnosis macular edema secondary to central retinal vein occlusion (CRVO) for no longer than 6 months with mean central subfield thickness ? 250 ?m on OCT.
- •\- An ETDRS BCVA of 20/40 to 20/320 (73 to 24 letters) in the study eye.
- •\- BCVA \>20/400 in the fellow eye.
- •\- Absence of significant cataract that could affect visual results.
- •\- Able to return for ALL clinic visits and complete all study\-related procedures.
- •\- Absence of other ocular diseases that could affect visual acuity.
- •\- Willingness to provide written informed consent.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
Exclusion Criteria
- •\- Previous anti\-VEGF therapy, photodynamic therapy or thermal laser in the study eye.
- •\- Recent cataract surgery (\<3 months) in the study eye.
- •\- Any concurrent ocular disease that could affect the final outcome (diabetic retinopathy, advanced glaucoma, pathologic myopia).
- •\- No scar, fibrosis, atrophy or hemorrage involving the center of the fovea
- •\- No RPE rip/tear involving the central fovea
- •\- Severe proliferative macular ischemia patients and iris rubeosis patients
- •\- Participation in any other interventional clinical trial
- •\- History of vitrectomy surgery, submacular surgery, or other surgical intervention for AMD in the study eye
- •\- Active intraocular inflammation in the study eye
- •\- History of cerebral vascular accident, myocardial infarction, transient ischemic attacks within 3 months of study enrollment.
Outcomes
Primary Outcomes
Not specified
Similar Trials
Recruiting
Phase 4
A clinical trial to study the safety and efficacy of Pulmosil (Sildenafil Injection) for the treatment of hypertension.Health Condition 1: null- Pulmonary Arterial Hypertension.CTRI/2016/11/007424Sun Pharmaceutical Industries Limited
Recruiting
Phase 2
A phase II study to evaluate the effectiveness of S-1 + Cetuximab for patients with advanced/recurrent colon cancer who cannot undergo intensive therapyadvanced/recurrent colon cancer patients with RAS wild-type tumors who cannot undergo intensive therapyJPRN-UMIN000018484HO HOKKAIDO CANCER CENTER Division of Gastroenterology57
Completed
Not Applicable
The effect of Indian ink on the identification of involved lymph nodes in breast cancerbreast cancer.Malignant neoplasm of breastIRCT20180720040533N3Tehran University of Medical Sciences20
Active, not recruiting
Phase 1
Study to evaluate the efficacy of OnabotulinumtoxinA in migraineEUCTR2017-002866-38-ITIRCCS FONDAZIONE ISTITUTO NEUROLOGICO NAZIONALE C. MONDINO42
Not yet recruiting
Not Applicable
Estimation of type of hearing loss using a new Forehead knuckle tapping methodCTRI/2021/01/030777Dr Prem Sagar