Understanding the Jaw Joint in Asymmetrical Faces: With or Without Jaw Pain

Not yet recruiting

• Conditions: Facial Asymmetry

• Registration Number: CTRI/2025/06/089180
• Lead Sponsor: Dr Desu Harshini

Brief Summary

**Morphological and Positional Assessment of Condyle in Facial Asymmetry Patients with or without Temporomandibular Disorders: A CBCT Study**

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**Background:**Facial asymmetry can influence not only dental occlusion but also the morphology and position of the temporomandibular joint (TMJ), possibly leading to temporomandibular disorders (TMD). Variations in condylar position and shape are believed to play a critical role in these conditions. Cone Beam Computed Tomography (CBCT) is a valuable diagnostic tool for evaluating these structures in three dimensions with reduced radiation exposure.

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**Aim:**To evaluate and compare the **positional and morphological changes of the mandibular condyle** in patients with facial asymmetry, with and without TMD, using CBCT.

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**Objectives:**

1. Assess condylar morphology and position in symmetrical patients without TMD (control group).

2. Assess the same parameters in asymmetrical patients with TMD.

3. Assess the same parameters in asymmetrical patients without TMD.

4. Compare findings across all three groups.

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**Study Design:**

- **Type**: Prospective, observational, multi-arm, cross-sectional study

- **Sample size**: 66 participants (22 in each group)

- **Grouping**: Based on presence of facial asymmetry and TMD

- **Method**: Clinical exam, validated TMD questionnaire, CBCT imaging

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**Primary Outcome:**

- Condylar positional and morphological parameters on CBCT, including joint spaces, condylar dimensions, and alignment.

**Secondary Outcome:**

- Association of condylar variations with facial asymmetry and presence/absence of TMD symptoms.

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**Time Points:**All outcomes are assessed **once at baseline**, during initial CBCT scan and questionnaire assessment.

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**Statistical Analysis:**

- Chi-square test

- ANOVA / Kruskal-Wallis test

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**Conclusion (anticipated):**This study aims to provide insights into how condylar morphology and position vary with facial asymmetry and TMD, potentially aiding in early diagnosis and treatment planning using CBCT.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2025-06-17
• Study Start: 2025-10-07

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 66

Inclusion Criteria

• Control group: Patients without mandibular asymmetry.
• No previous orthodontic treatment Patients greater than 18 years of age.
• Full permanent dentition.
• Experimental group: Patients with mandibular asymmetry greater than 2mm.
• No previous orthodontic treatment.
• Patients greater than 18 years of age.

Exclusion Criteria

• TMJ -Trauma/surgery/Fracture.
• Treatment with occlusal splints.
• Previous orthodontic treatment.
• Prosthetic crowns and bridges.
• Orthognathic surgery.
• Missing / malformed teeth/supernumerary teeth.
• Congenital / Systemic disorders.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Condylar angle to mid-sagittal plane	6 months
Distance of condylar center to midline	6 months
Condylar position within the glenoid fossa:	6 months
Asymmetry in geometric position between right and left condyles	6 months
Condylar morphology:	6 months
Anterior, superior, and posterior joint spaces	6 months
Depth of mandibular fossa	6 months
Anteroposterior and mediolateral diameters	6 months

Secondary Outcome Measures

Name	Time	Method
Association between condylar changes and presence of facial asymmetry and/or TMD symptoms.	This includes:

Trial Locations

Locations (1)

GSL dental college and hospital; 🇮🇳 Godavari, ANDHRA PRADESH, India

GSL dental college and hospital

🇮🇳Godavari, ANDHRA PRADESH, India

DrDesu Harshini

Principal investigator

09182263613

drdesuharshini@gmail.com