Memokath in ureteric stricture study

Not Applicable

• Conditions: Intractable ureteric obstruction; Urological and Genital Diseases

• Registration Number: ISRCTN69157693
• Lead Sponsor: South Tees Hospitals NHS Foundation Trust

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-01-31
• Last Update Posted: 17 April 2023
• Study Completion: 2026-09-30

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1. Dependent on JJ stent for management of unilateral or bilateral ureteric obstruction
2. Benign or malignant obstruction
3. Life expectancy of more than 2 years
4. Renal unit function of more than 20, as assessed by nuclear medicine scan
5. Normal ureter below and above the level of obstruction as observed by retrograde pyelogram or ureteroscopy
6. Stricture not suitable or patient unfit for reconstructive surgery (OR patient choice as documented in clinic letter or medical notes)
7. Fit to undergo retrograde MK-051 insertion under general or regional anaesthesia

Exclusion Criteria

1. Age less than 18 years
2. Allergy to nickel
3. Renal unit function less than 20, as assessed by nuclear medicine scan
4. Pelvic ureteric junction (PUJ) involved in stricture
5. Vesico-ureteric junction (VUJ) involved in stricture
6. Primary PUJ obstruction or Mega Ureter
7. Not on JJ stent
8. Life expectancy less than 2 years
9. Previous active stone (stones present in the kidney, metabolic stone disease, forming stones within 2 years before recruitment)
10. Disease that requires ureteric instrumentation for treatment
11. Lack of capacity

Study & Design

• Study Type: Interventional
• Study Design: Not specified