Arterial Hypotension and Regional Cerebral Oxygen Saturation During Major Abdominal Surgery. A Randomized Controlled Trial
Overview
- Phase
- Not Applicable
- Intervention
- HPI
- Conditions
- Hypotension During Surgery
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- Enrollment
- 48
- Locations
- 1
- Primary Endpoint
- Cerebral tissue oximetry
- Status
- Completed
- Last Updated
- 2 months ago
Overview
Brief Summary
In this study investigators will explore the association between intraoperative arterial hypotension and cerebral oxygen saturation in patients scheduled for major abdominal surgery. Investigators will assign patients to control or interventional group. In this last group arterial hypotension will be avoided based on a HPI (Hypotension Predictive Index) protocol. In the control group arterial hypotension will be promptly treated according to hemodynamic variables.
Investigators
RUSSO ANDREA
Principal Investigator
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Eligibility Criteria
Inclusion Criteria
- •patients scheduled for abominal surgery
Exclusion Criteria
- •Emergency surgery
- •end-stage renal disease
- •pregnancy
- •atrial fibrillation
- •previous cerebral ischaemia
- •central nervous system disorders
Arms & Interventions
prevention
investigator will prevent intraoperative arterial hypotension based on HPI index
Intervention: HPI
treatment
investigators will treat intraoperative arterial hypotension based on standard hemodynamic parameters
Outcomes
Primary Outcomes
Cerebral tissue oximetry
Time Frame: immediately after surgery
the difference among the two groups of the percentage value of the median value of Cerebral Oxygen Saturation measured by the near-nfrared spectroscopic technology (Foresight sensor)