Early Warning Model Construction on Cognition, Resistance and Using Risk of the New Psychoactive Substances in Adolescents Based on Behavioral Expression of Addiction Susceptibility Genes and Adverse Childhood Experience
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- the resistance of NPS
研究概览
简要总结
Based on the biological-psychology-sociological medicine pattern, this study aims to construction an early warning model of the New Psychoactive Substances (NPS) using for adolescents aged 14-35 years old. This study intends to obtain the data related to the behavioral expression of addiction susceptibility genes, adverse childhood experience, cognition, resistance and the use of NPS in adolescents by questionnaire survey (sample size: 200), and then use logistic regression and machine learning to construct an early warning model.
详细描述
Based on the biological-psychology-sociological medicine pattern, this study aims to construction an early warning model on the use of the New Psychoactive Substances using for adolescents aged 14-35 years old. This study intends to conduct a questionnaire survey (sample size 200) to obtain data related to the behavioral expression of addiction susceptibility genes, childhood adversity experience, cognition, resistance and the use of NPS in adolescents from different regions and different populations. Through data analysis, this study aims to get the weight of different risk factors on NPS use, and then use logistic regression and machine learning to construct an early warning model, so as to screen out high-risk groups. At the same time, the expert group was consulted to establish a risk early warning system to provide a basis for intervention.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 14 Years 至 35 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adolescents aged 14-35 (including 14,35 years old)
- •Agree to participate in the studies
排除标准
- •Be diagnosed with psychological or mental illness
- •People that are unconscious, emotionally unstable, or unable to communicate normally
- •Patients with severe diseases
结局指标
主要结局
the resistance of NPS
时间窗: Baseline
the drug refusal self-efficacy scale and the drug use permissive attitude will be used to measure the the resistance of NPS
the use of NPS
时间窗: Baseline
there will be some questions to investigate the drug use conditions
Adverse Childhood Experience
时间窗: Baseline
the Chinese version of Adverse Childhood Experience Scale with 10 items will be used to measure the adverse childhood experience
externalizing behavior
时间窗: Baseline
17 items of aggressive behavior and 15 items of rule-breaking behavior from the Chinese Version of Achenbach Youth Self-Report-2001 Version will be used to measure adolescents' degree of externalizing behavior
sleep quality
时间窗: Baseline
the Pittsburgh Sleep Quality Index with 9 items will be used to measure adolescents' sleep quality
hedonic hunger
时间窗: Baseline
the Power of Food Scale with 15 items will be used to measure hedonic hunger
the cognition of NPS
时间窗: Baseline
knowledge questionnaire of drug types and risk awareness of drug use will be investigated to know the degree of cognition to NPS
sensation seeking personality
时间窗: Baseline
the Brief Sensation Seeking Scale for Chinese with 8 items will be used to measure sensation seeking personality
prosocial behavior
时间窗: Baseline
the Prosocial Tendencies Measure with 26 items will be used to measure prosocial behavior
次要结局
未报告次要终点
研究者
Wei XIA, PhD
Associate Professor
Sun Yat-sen University