Effect of fibrinogen compared to fresh frozen plasma on patients with hemorrhagic shock

Phase 3

Completed

• Conditions: Condition 1: Hemorrhagic shock. Condition 2: Hypovolemic shock.; Hemorrhage, not elsewhere classified; Hypovolemic shock; R57.1

• Registration Number: IRCT20150704023046N4
• Lead Sponsor: Ahvaz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 24 February 2020

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Patients with hemorrhagic shock caused by multiple trauma
Age> 14 years
Systolic blood pressure <90 mm Hg
Significant chance of bleeding
Evidence of intra abdominal bleeding
Clinical judgment of the doctor about the receipt of blood products

Exclusion Criteria

Pregnancy
Patients with known coagulopathy
Using anti-coagulant and anti-platelet drugs
Other causes of shock, such as neurogenic shock
Previous history of blood product in the last 6 months
Patients are severely ill, whose priority is to preserve the patient's health
Dissatisfaction with the patient or patient companions to participate in the study

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Blood Pressure. Timepoint: 4 and 12 hours after admission, 24-hour short-term prognosis, 7-day mid-term and long-term 28-day. Method of measurement: Clinical examination and assessment of vital signs by cardiac monitoring and pulse oximetry located in the cardiopulmonary resuscitation room.;Oxygenation index. Timepoint: 4 and 12 hours after admission, 24-hour short-term prognosis, 7-day mid-term and long-term 28-day. Method of measurement: pulse oximetry located in the cardiopulmonary resuscitation room.;PH level. Timepoint: 4 and 12 hours after admission, 24-hour short-term prognosis, 7-day mid-term and long-term 28-day. Method of measurement: By taking arterial blood samples and evaluating arterial blood gas by laboratory tests.;Duration of admission. Timepoint: When ordering a patient's discharge or issuing a death certificate. Method of measurement: Clinical examination and evaluation of patient records.