Combined Physical and Psychological Intervention in Carpal Tunnel Syndrome Patients With Nociplastic Pain

Not Applicable

Recruiting

• Conditions: Pain, Chronic; Carpal Tunnel Syndrome
• Interventions: Other: Combined physical and psychological intervention; Other: Standard care

• Registration Number: NCT05915611
• Lead Sponsor: Ahram Canadian University

Brief Summary

To assess the effectiveness of a combined physical and psychological intervention in reducing pain and improving function in carpal tunnel syndrome patients with nociplastic pain.

Detailed Description

Not available

Study Timeline

• Status Verified: 2023-06
• Study First Submitted: 2023-06-14
• Study First Submitted QC: 2023-06-14
• Last Update Submitted: 2023-06-14
• Study First Posted: 2023-06-23
• Last Update Posted: 2023-06-23
• Study Start: 2023-06-27
• Primary Completion: 2024-09-27
• Study Completion: 2024-09-27

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 64

Inclusion Criteria

• Adults aged 25-65 years
• Both sexes
• Diagnosis of carpal tunnel syndrome based on clinical examination and nerve conduction studies
• Presence of nociplastic pain as determined by the Central Sensitization Inventory (CSI) with a score ≥40
• Positive tinel and phalen sign.

Exclusion Criteria

• Previous carpal tunnel release surgery
• Other musculoskeletal or neurological disorders affecting the upper extremity

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Intervention group	Combined physical and psychological intervention	Participants will receive a twelve-week combined physical and psychological intervention.
Control group	Standard care	Participants will receive a twelve-week of standard care of splinting, tendon and nerve gliding exercises.

Primary Outcome Measures

Name	Time	Method
Pain intensity using the Numeric Pain Rating Scale (NPRS)	Changes in pain intensity at baseline, 6 weeks, 12 weeks.
Median nerve sensory distal latency	Changes in Median nerve sensory distal latency at baseline, 6 weeks, 12 weeks.
Functional ability using the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire	Changes in Functional ability at baseline, 6 weeks, 12 weeks.
Median nerve motor distal latency	Changes in Median nerve motor distal latency at baseline, 6 weeks, 12 weeks.

Secondary Outcome Measures

Name	Time	Method
Pain catastrophizing using the Pain Catastrophizing Scale (PCS)	Changes in Pain Catastrophizing Scale (PCS) at baseline, 6 weeks, 12 weeks.
Fear of movement using the Tampa Scale for Kinesiophobia (TSK)	Changes in Tampa Scale for Kinesiophobia (TSK) at baseline, 6 weeks, 12 weeks.
Grip strength measured using a hand dynamometer	Changes in Grip strength at baseline, 6 weeks, 12 weeks.

Trial Locations

Locations (1)

Outpatient clinic of faculty of physical therapy, Ahram Canadian University; 🇪🇬 Al Ḩayy Ath Thāmin, Giza, Egypt