Combined Physical and Psychological Intervention in Carpal Tunnel Syndrome Patients With Nociplastic Pain

Not Applicable

Recruiting

• Conditions: Pain, Chronic; Carpal Tunnel Syndrome

• Registration Number: NCT05915611
• Lead Sponsor: Ahram Canadian University

Brief Summary

To assess the effectiveness of a combined physical and psychological intervention in reducing pain and improving function in carpal tunnel syndrome patients with nociplastic pain.

Detailed Description

Not available

Study Timeline

• Status Verified: 2023-06
• Study First Submitted: 2023-06-14
• Study First Submitted QC: 2023-06-14
• Last Update Submitted: 2023-06-14
• Study First Posted: 2023-06-23
• Last Update Posted: 2023-06-23
• Study Start: 2023-06-27
• Primary Completion: 2024-09-27
• Study Completion: 2024-09-27

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 64

Inclusion Criteria

• Adults aged 25-65 years
• Both sexes
• Diagnosis of carpal tunnel syndrome based on clinical examination and nerve conduction studies
• Presence of nociplastic pain as determined by the Central Sensitization Inventory (CSI) with a score ≥40
• Positive tinel and phalen sign.

Exclusion Criteria

• Previous carpal tunnel release surgery
• Other musculoskeletal or neurological disorders affecting the upper extremity

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Pain intensity using the Numeric Pain Rating Scale (NPRS)	Changes in pain intensity at baseline, 6 weeks, 12 weeks.
Median nerve sensory distal latency	Changes in Median nerve sensory distal latency at baseline, 6 weeks, 12 weeks.
Functional ability using the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire	Changes in Functional ability at baseline, 6 weeks, 12 weeks.
Median nerve motor distal latency	Changes in Median nerve motor distal latency at baseline, 6 weeks, 12 weeks.

Secondary Outcome Measures

Name	Time	Method
Pain catastrophizing using the Pain Catastrophizing Scale (PCS)	Changes in Pain Catastrophizing Scale (PCS) at baseline, 6 weeks, 12 weeks.
Fear of movement using the Tampa Scale for Kinesiophobia (TSK)	Changes in Tampa Scale for Kinesiophobia (TSK) at baseline, 6 weeks, 12 weeks.
Grip strength measured using a hand dynamometer	Changes in Grip strength at baseline, 6 weeks, 12 weeks.

Trial Locations

Locations (1)

Outpatient clinic of faculty of physical therapy, Ahram Canadian University; 🇪🇬 Al Ḩayy Ath Thāmin, Giza, Egypt