NCT07240051CompletedNot Applicable
Assessment of the Efficacy and Safety of 50% Glycolic Acid, 30% Salicylic Acid, and Modified Jessner's Chemical Peels in the Treatment of Active Acne and Post-acne Hyperpigmentation: Randomized Controlled Trial
Nahla Maher Mahmoud Mahran1 site in 1 country90 target enrollmentStarted: March 9, 2024Last updated:
Conditions
Interventions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 90
- Locations
- 1
- Primary Endpoint
- improvement in acne vulgaris by assessing Global acne scoring system and post-acne hyperpigmentation index
Study Overview
Brief Summary
Assessment of the Efficacy and Safety of 50% Glycolic Acid, 30% Salicylic Acid, and Modified Jessner's Chemical Peels in the Treatment of Active Acne and Post-acne Hyperpigmentation: Randomized Controlled Trial.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Triple (Participant, Investigator, Outcomes Assessor)
Eligibility Criteria
- Ages
- — to 65 Years (Child, Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Facial active acne (mild and moderate cases)
- •post-acne hyperpigmentation
- •a minimum age of 18 years
- •skin phototype III or IV
Exclusion Criteria
- •Pregnant or nursing women
- •active infection in the treatment area (e.g., verrucae and herpes simplex)
- •systemic disease (hypertension, diabetes, or bleeding tendency)
- •systemic retinoid or laser treatment within the last 6 months
- •history of keloidal tendency or Aspirin sensitivity.
Arms & Interventions
glycolic acid group
Active Comparator
30 patients received 50% glycolic acid peels
Intervention: Glycolic acid peel alone (Procedure)
Modified Jessener group
Active Comparator
30 patients received MJ peel
Intervention: modified jessener (Procedure)
Salicylic acid group
Active Comparator
30 patients received Salicylic acid 30%
Intervention: salicylic acid (Procedure)
Outcomes
Primary Outcomes
improvement in acne vulgaris by assessing Global acne scoring system and post-acne hyperpigmentation index
Time Frame: 6 months
Secondary Outcomes
No secondary outcomes reported
Investigators
Nahla Maher Mahmoud Mahran
lecturer of Dermatology
Cairo University
Study Sites (1)
Loading locations...
Similar Trials
Not yet recruiting
Not Applicable
comparison of chemical peel versus tranexamic acid tablet for treatment of facial pigmentatioCTRI/2022/07/044452Military hospital
Completed
Not Applicable
Glycolic Acid Plus Salicylic Acid in Treatment of Plane WartPlane WartNCT06233019Assiut University100
Completed
Not Applicable
Comparison of use of glycolic acid and salicylic acid peel in acne(pimples).CTRI/2018/06/014615Department of Dermatology70
Completed
Not Applicable
Treatment of Acne scarsCTRI/2018/02/012050Andrea Rosario30
Completed
Not Applicable
The effectiveness of plyglycolic acid felt (Neoveil(R)) for preveontion of Frey's syndrome after parotidectomyFrey's syndromeJPRN-UMIN000031066Department of plastic and reconstructive surgery, National Defense Medical College20