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Clinical Trials/NCT03833284
NCT03833284
Completed
Not Applicable

Implementation of a Transvaginal Ultrasound Surveillance Program in Women With a History of Previous Preterm Birth: Disseminating Evidenced Based Practices for Reducing Preterm Birth in Appalachian Kentucky

Niraj Chavan1 site in 1 country56 target enrollmentJune 3, 2019
ConditionsPreterm Birth

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Preterm Birth
Sponsor
Niraj Chavan
Enrollment
56
Locations
1
Primary Endpoint
Change in attitudes towards TVU screening among patients and practitioners
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

Preterm Birth is the number one cause of infant morbidity and mortality worldwide and represents an important health disparity in the United States, particularly across the state of Kentucky. The best biomarker for the prediction of preterm birth is transvaginal ultrasound (TVU). This study will attempt to identify and rectify provider and patient related barriers to TVU screening implementation.

Detailed Description

Preterm birth is the number one cause of infant morbidity and mortality worldwide and represents an important health disparity in the United States, and especially across the state of Kentucky. The best biomarker for the prediction of preterm birth is transvaginal ultrasound (TVU) measurement of cervical length. However, several unique provider and patient related barriers for implementation of this screening limit the widespread uptake of this evidence based practice in Appalachian KY. The investigators propose to adopt a dissemination and implementation science approach using the Consolidated Framework for Implementation Research (CFIR) as the guiding framework for identification of key areas of knowledge deficits as well as attitudes, practices and perceived barriers among prenatal care providers and patients in eastern KY towards TVU cervical length screening using a mixed - methods design. This will be utilized to develop a multifaceted implementation strategy best suited for addressing and overcoming barriers identified by the target population in eastern KY. The investigators anticipate that such an implementation strategy will likely include an educational component targeting obstetric care providers and patients in addition to hands-on TVU cervical length evaluation as well as telemedicine support and surveillance. Three community based sites (Hazard, Morehead and Ashland, KY) will be recruited for implementation of this multi-component pilot program focused on community engagement and outreach targeting obstetric providers and their patients. At the end of the pilot implementation phase, acceptability of the study intervention and feasibility of implementation will be evaluated along with a preliminary assessment of effectiveness of implementation.

Registry
clinicaltrials.gov
Start Date
June 3, 2019
End Date
October 29, 2021
Last Updated
4 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Niraj Chavan
Responsible Party
Sponsor Investigator
Principal Investigator

Niraj Chavan

Assistant Professor in Maternal Fetal Medicine

University of Kentucky

Eligibility Criteria

Inclusion Criteria

  • Participant
  • Female Sex
  • Prior history of preterm birth (for initial set of interviews), no preterm birth history required for intervention feedback
  • Current pregnant status

Exclusion Criteria

  • Participant
  • Inclusion Criteria: Provider
  • Certified as obstetric/gynecologic provider

Outcomes

Primary Outcomes

Change in attitudes towards TVU screening among patients and practitioners

Time Frame: At baseline and at one year.

The primary purpose of this study is to evaluate the change in attitudes towards TVU screening among patients and practitioners. This will be accomplished by conducting a qualitative interview with each participant at baseline and again at one year (after completing the CLEAR program workshop).

Potential for future TVU screening implementation based on changes in attitudes towards TVU screening among providers and participants.

Time Frame: At baseline and at one year.

The primary purpose of this study is to evaluate the change in attitudes towards TVU screening among patients and practitioners. This will be accomplished by conducting a qualitative interview with each participant at baseline and again at one year (after completing the CLEAR program workshop). Analysis of these interviews will aid in determining feasibility of implementing a future TVU screening component in Obstetric and Gynecologic care.

Secondary Outcomes

  • Rate of inpatient hospitalization for preterm labor management prior to delivery(Through study completion, average of 1 year from study initiation.)
  • Rate of preterm birth at <34 weeks gestation(Through study completion, average of 1 year from study initiation)
  • Rate of preterm birth at <37 weeks gestation(Through study completion, average of 1 year from study initiation)
  • Number of TVU scans identifying a short cervix (≤ 25 mm) in any pregnant women at each study site(Through study completion, average of 1 year from study initiation.)
  • Rates of clinical therapy(Through study completion, average of 1 year from study initiation.)

Study Sites (1)

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