NCT01850459已完成不适用
Extracellular Signal-Related Kinase Biomarker Development in Autism
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 213
- 试验地点
- 1
- 主要终点
- ERK activation
研究概览
简要总结
The purpose of this research study is to establish a way to help the development of targeted treatments in autism spectrum disorders. This may also help in early diagnosis of autism and may possibly predict severity. The study will compare subject's ERK (extracellular signal-related kinase) signaling to age- and gender-matched neurotypical controls and Intelligence quotient (IQ)-matched developmental disabilities.
详细描述
Autism Spectrum Disorder Subject Criteria:
Inclusion Criteria:
- Diagnosis of autism spectrum disorder, based upon a clinical interview utilizing the Diagnostic and Statistical Manual-V (DSM-V)
- Age 3-25 years
- Stable dosing of psychotropic drugs for greater than or equal to 5 half-lives
Exclusion Criteria:
- Diagnosis of schizophrenia, another psychotic disorder, bipolar disorder, or alcohol or other substance abuse based on Diagnostic and Statistical Manual-V criteria
- Use of lithium, riluzole or other known modulators of ERK activation
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 3 Years 至 25 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
ERK activation
时间窗: Up to three years
次要结局
未报告次要终点
研究者
研究点 (1)
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