Comparing the Efficacy of Hydrogen Peroxide Versus Normal Saline in Postoperative Care of Sutured Wounds
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Irritation scale rating from 1-2 weeks compared to baseline
研究概览
简要总结
The primary objective of this study is to compare the efficacy of hydrogen peroxide versus normal saline in postoperative care of sutured wounds. Subjects will be randomly assigned to standard of care hydrogen peroxide or standard of care normal saline in postoperative care of sutured wounds followed by applying petroleum jelly and sterile gauze bandage. Data will be collected at day 0 and between days 7 to14. Subjects will provide irritation scale rating (0-4) with 0 being none/absent and 4 being severe/extreme.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients who are undergoing sutured wound after dermatologic procedure.
- •Males and females ages 18-65 years old.
- •Patients who are in good health.
- •Willingness and the ability to understand and provide informed consent and communicate with the investigator/study staff.
排除标准
- •History of keloids or hypertrophic scars.
- •History of bleeding tendency or coagulopathy.
- •Pregnant or lactating or intends to become pregnant in the next 3 months.
- •Active skin disease or skin infection in the treatment area.
- •Unable to understand the protocol or to give informed consent.
- •Any other condition that would, in the professional opinion of the investigator, potentially affect response or participation in the clinical clinical study, or would pose as an unacceptable risk to the subject.
研究组 & 干预措施
Saline
Post-operative wound will be treated with 0.9% normal saline. Subjects will also clean the sutured wounds with normal saline twice daily then dress the wounds with petroleum jelly and a bandage.
干预措施: 0.9% normal saline (Drug)
Hydrogen Peroxide
Post-operative wound will be treated with 3% H2O2 solution, Subjects will also clean the sutured wounds with 3% H2O2 solution or twice daily then dress the wounds with petroleum jelly and a bandage.
干预措施: 3% H2O2 solution (Drug)
结局指标
主要结局
Irritation scale rating from 1-2 weeks compared to baseline
时间窗: Baseline and 1-2 weeks
Subjects will provide irritation scale rating (0-4) with 0 being none/absent and 4 being severe/extreme.
次要结局
未报告次要终点
研究者
Murad Alam
Professor in Dermatology, Otolaryngology-Head and Neck Surgery, and Surgery
Northwestern University