COMPARATIVE EVALUATION OF PAIN AFTER ROOT CANAL TREATMENT WITH AND WITHOUT USING LASERS FOR DISINFECTION OF ROOT CANALS

Completed

• Conditions: Symptomatic Apical Periodontitis; Acute apical periodontitis of pulpal origin,

• Registration Number: CTRI/2021/03/031957
• Lead Sponsor: Dr Shreya Shivangi

Brief Summary

Pain management is one of the most important aspects of endodontic treatment. Infected root canals are the most common cause of endodontic pain. Pain may also be induced following conventional endodontic therapy and even with recently available techniques total eradication of the bacteria is almost unachievable. In the recent years, use of diode lasers has gained acceptance in the endodontic field. It was found by Pawar et al. and Bjordal et al. that the diode laser acted on pain and had an anti-inflammatory effect by decreasing PGE2, bradykinin, acetylcholine, histamine, serotonin, and substance P. In earlier studies related to lasers, the use of lasers was limited to treating dentinal hypersensitivity, for its effects on vital pulpotomy, and for evaluating postoperative pain and swelling in patient undergoing extractions of impacted 3rd molar. Lately, studies performed for evaluating post-operative endodontic pain using lasers showed varying results of significant differences between control groups and test group as well as comparable differences between the two. Therefore, it remains debatable whether laser therapy is effective in reducing post-operative pain after endodontic treatment or not. According to our literature search, we found only a few studies evaluating the use of lasers for post-operative endodontic pain reduction which were mostly for the International populations. Also, to the best of our knowledge, Biolase EpicX and Pro HS Niti Rotary systems have not been used in the investigations for the same. Therefore, this clinical study proposes to investigate the incidence of post-operative pain following chemo-mechanical preparation of single rooted teeth (using Pro HS Niti Rotary systems) having symptomatic apical periodontitis with and without laser irradiation (by Biolase EpicX) for the Indian population.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-03-20
• Study Completion: 2021-09-23
• Last Update Posted: 2021-12-23

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Subjects older than 18 years of either gender.
• Subjects having a single rooted non-vital tooth with symptomatic apical periodontitis needing primary endodontic treatment.
• Cooperative health subjects who are willing to participate in the study and sign the consent form.

Exclusion Criteria

• Subjects with uncontrolled systemic diseases or allergies.
• History of previous root canal treatment.
• Presence of swelling or sinus tracts.
• Presence of severe periodontal disease.
• Periapical radiolucency.
• Subjects who’ve taken analgesics within the last 3 days.
• Subjects allergic to local anesthesia.
• Subjects unwilling to sign the consent form.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Post operative pain scores	Post operative pain scores at 24 hours, 48 hours, and 72 hours

Secondary Outcome Measures

Name	Time	Method
Percussion pain scores	Pre-operative percussion pain score and post - operative percussion pain score (at 72 hours)

Trial Locations

Locations (1)

Bharati Vidyapeeth Dental College and Hospital, Sector 7, CBD Belapur, Navi Mumbai; 🇮🇳 Mumbai, MAHARASHTRA, India

Bharati Vidyapeeth Dental College and Hospital, Sector 7, CBD Belapur, Navi Mumbai

🇮🇳Mumbai, MAHARASHTRA, India

Dr Shreya Shivangi

Principal investigator

8310270967

shivangi.shreya@gmail.com