Reversal of neuromuscular block using sugammadex
- Conditions
- The effect of sugammadex dose on residual neuromuscular blockade will be investigated, therefore patients suffering from various conditions undergoing surgery in general anaesthesia with muscle relaxation will be included in the study.Therapeutic area: Body processes [G] - Physiological processes [G07]
- Registration Number
- EUCTR2011-001683-22-HU
- Lead Sponsor
- niversity of Debrecen, Medical and Health Science Center, Department of Anaesthesiology and Intensive Therapy
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Authorised-recruitment may be ongoing or finished
- Sex
- All
- Target Recruitment
- Not specified
1. Pateint aged 18-65 undergoing general surgery in neuromuscular blockade
2. ASA (American Society of Anesthesiology) physical status score 1-3
3. BMI (Body-Mass Index) 18,5-25
4. duration of operation over 50 minutes
5. need for intratracheal intubation
6. supine position, at least one arm accessible.
Are the trial subjects under 18? no
Number of subjects for this age range: 0
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 80
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
1. diseases influencing neuromuscular function (myopathies, significant renal or hepatic insufficiency)
2. drugs influencing neuromuscular function (magnesium, aminoglycosides)
3. gravidity
4. urgent surgery
5. chronic obstructive pulmonary disease
6. bronchial asthma
7. glaucoma
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method