Clinical and sonological correlation between the distance of the tumour to the nipple-areola complex with axillary nodal involvement in a case of Carcinoma of the breast.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 35
- 试验地点
- 1
- 主要终点
- The decision to perform or avoid axillary clearance can be determined by assessing the tumor location and measuring the distance between the tumor and the nipple-areolar complex.
研究概览
简要总结
Breast cancer stands as the most prevalent form of cancer among women. This type of cancer often advances without noticeable symptoms, making routine screenings or self-examinations crucial for its detection. We hope to analyse whether tumour location (quadrants) and tumour–nipple distance can help in predicting axillary node positivity by using current data of patients that will be a part of our cross-sectional observational study. will be conducted on patients with Carcinoma of the breast, primarily T1 and T2 patients, according to the 8th A.J.C.C Classification of T.N.M staging. In this study, 35 patients will be included and the outcomes will be recorded and analysed at the end of the study. we aimto determine the correlation between the mean distance of the tumour and nipple-areola complex and nodal positivity of axillary lymph nodes. If we can demonstrate a correlation, this study may help to prevent needless axillary nodal dissection procedures. It could also help to reduce the expense of the sentinel lymph node biopsy equipment and therapy.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- Female
入选标准
- •1.Patients admitted at A.V.B.R.H for lump in breast.
- •2.Female patients aged 18 or older.
- •3.Female breast cancer patients exhibiting intact, uninvaded skin of the nipple and areola.
- •4.Individuals diagnosed pathologically and radiologically with early-stage invasive breast cancer, devoid of distant metastasis.
- •5.Patients who have not previously undergone neoadjuvant chemotherapy, endocrine therapy, or targeted therapy.
- •6.Patients who express willingness to undergo Modified Radical Mastectomy.
- •7.Patients with no history of prior breast or axillary surgery.
排除标准
- •Pregnant status Prior occurrence of any malignant tumor within the last five years History of previous breast surgery Diagnosis of multi-center, multifocal, or bilateral breast cancer, as well as ductal carcinoma in situ The presence of severe systemic illness or dysfunction in any organ Patients currently receiving or having received adjuvant chemotherapy, endocrine therapy, or targeted therapy.
结局指标
主要结局
The decision to perform or avoid axillary clearance can be determined by assessing the tumor location and measuring the distance between the tumor and the nipple-areolar complex.
时间窗: 3 month pre and post operative period
次要结局
- n/a(n/a)