A single-blind and crossover study examining the efficacy of intranasal oxytocin administration for social impairments in subjects with pervasive developmental disorders
Not Applicable
Recruiting
- Conditions
- Pervasive developmental disorders
- Registration Number
- JPRN-UMIN000005809
- Lead Sponsor
- Department of Neuropsychiatry, Showa University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Male
- Target Recruitment
- 60
Inclusion Criteria
Not provided
Exclusion Criteria
1) History of allergy for oxytocin 2) Cannot enter Magnetic Resonance Scanner 3) History of traumatic brain injury with any known cognitive consequences or loss of consciousness for more than 5 minutes 4) History of substance abuse or addiction 5) Instabilized with psychiatric comorbidity
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method psychological tasks related to social skills (face and facial expression recognition task, inference task utilizing social context), NIRS and eye tracking data
- Secondary Outcome Measures
Name Time Method self rating scales, such as AQ(Autism Quatient), PARS(Pervasive Developmental Disorders Autism Society Japan Rating Scale), EPQ(Eysenck personality questionnaire), SPQ(Schizotypal Personality Questionnaire), TCI(Schizotypal Personality Questionnaire),SIQ(Social Intelligence Quantity)