Efficacy of Hyaluronic Acid Gel and Photobiomodulation on Wound Healing After Surgical Gingivectomy: a Randomized Controlled Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 26
- 试验地点
- 1
- 主要终点
- Wound healing
研究概览
简要总结
The aim of this study was to evaluate the effect of hyaluronic acid gel after photobiomodulation on the healing of surgical gingivectomy sites
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Chronic inflammatory gingival enlargement grade 2 and 3 according to the gingival overgrowth index by Miller and Damn.
- •Adequate amount of keratinized tissue.
- •Attachment loss= 0
- •Well educated patients as post-operative instructions need to be followed precisely.
排除标准
- •Patients with history of smoking
- •Pregnant women
- •Patients with bad oral hygiene
- •Patients who have any known systemic disease that interfere with performance of surgical gingivectomy or periodontal wound healing
- •Patients who have any previous adverse reactions to the products (or similar products) used in this study
研究组 & 干预措施
Photobiomodulation
干预措施: Photobiomodulation (Device)
Hyaluronic acid gel after photobiomodulation
干预措施: Hyaluronic acid after photobiomodulation (Other)
结局指标
主要结局
Wound healing
时间窗: up to 21 days
Assessed using Landry's healing index which grades the wound on a scale of 1 (poor) to 5 (excellent) * Very poor (1): ≥50% of gingiva red, bleeding on palpation, Granulation tissue present, Non-epithelialized incision margin with loss of epithelium beyond the margin. * Poor (2): ≥50% of gingiva red, bleeding on palpation, Granulation tissue present, Non-epithelialized incision margin with exposed connective tissue * Good (3): ≥25% and\<50% of gingiva red, No bleeding on palpation, no granulation tissue, No exposed connective tissue on the incision margin * Very good (4): \<25% of gingiva red, No bleeding on palpation, no granulation tissue, No exposed connective tissue on the incision margin * Excellent (5): All tissues are pink, No bleeding on palpation, no granulation tissue, No exposed connective tissue on the incision margin
Perceived pain
时间窗: up to 21 days
This was assessed using Visual Analogue Scale (VAS). Patients were instructed to chart their perceptions of pain using VAS ranging from 0-10; where 0 represents no pain/burning sensation and 10 represents severe pain/burning sensation.
次要结局
未报告次要终点
研究者
Basma Khalil
Resident of Periodontology
Alexandria University