Accuracy of Aspergillus Immunohistochemistry for Diagnosis of Aspergillosis

Not Applicable

• Conditions: - Antigenic loss in Formalin- embedded (FFPE): Solution by choosing competent FFPE for immunostain and PCR for fungus - immunohistochemistry; fixed paraffin- A negative result of PCR for fungus: Solution by selected optima; Aspergillus; accuracy

• Registration Number: TCTR20191106003
• Lead Sponsor: Ratchadapiseksompotch Fund, Faculty of Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-11-06
• Study Completion: 2019-11-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Enrolling by invitation
• Sex: All
• Target Recruitment: 81

Inclusion Criteria

- The case of which diagnosis as aspergillosis could be performed from 2017 to 2018.
- Have H&E slide, paraffin block and complete pathological report from 2017 to 2018

Exclusion Criteria

- No H&E slide or paraffin block for immunostain or panfungal PCR.
- Cases in which immunostain or panfungal PCR could not be performed, i.e., small amount of tissue.
- Inadequate clinical history, i.e., unknown site.
- Inadequate pathological report, i.e., not describe feature of organism.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Accuracy of anti- aspergillus antibody 18 month sensitivity and specificity

Secondary Outcome Measures

Name	Time	Method
/A N/A N/A