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临床试验/NCT07067593
NCT07067593尚未招募不适用

Benefits and Risks of Amnioreduction for Management of Pregnant Women With Polyhydramnios

Assiut University1 个研究点 分布在 1 个国家目标入组 28 人开始时间: 2025年8月1日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
28
试验地点
1
主要终点
Gestational age at delivery

研究概览

简要总结

The aim of this work is to review the indications, procedural complications and outcomes of amnioreduction in pregnancies complicated by polyhydramnios.

详细描述

Polyhydramnios is the presence of excessive amniotic fluid in the amniotic sac and it's prevalence reaches 2% of all pregnancies . Polyhydramnios is diagnosed based on ultrasound criteria, as an amniotic fluid index (AFI) >25 cm or maximal vertical pocket > 8 cm . There is a recognized association of polyhydramnios and adverse pregnancy outcomes, including perinatal death, fetal abnormality and preterm birth . Management of the pregnancy can be problematic, particularly in severe cases, due to issues surrounding maternal discomfort and the risk of preterm birth. Amnioreduction, widely used in the management of polyhydramnios, is an option available to palliate maternal symptomatology and potentially prolong the pregnancy . Previous publications have shown a reduction in the risk for premature rupture of membranes and preterm labor decrease, placental perfusion improvement, and relief of maternal discomfort following amnioreduction

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

性别
Female
接受健康志愿者

入选标准

  • Pregnant women 20- 38 weeks
  • Patients with polyhydramnios
  • Exclusion criteria:
  • Lethal fetal anomalies
  • Pre labor rupture of membranes
  • Placental separation
  • Chorioamnionitis

排除标准

  • 未提供

结局指标

主要结局

Gestational age at delivery

时间窗: 4 months

Determine Gestational age at delivery in polyhydramnios patients . Increased age is good.

Rate of PROM

时间窗: 4 months

Number of cases developed PROM

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mohamed Gamal M.fekry

Lecturer obstetric and gynecology, Specialist Urogynecology

Assiut University

研究点 (1)

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