The Clinical Application of Adipose-Derived Stem Cells on Facial Rejuvenation
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 50
- 主要终点
- The therapeutic evaluation of adipose-derived stem cells or fat cells solely on facial rejuvenation
研究概览
简要总结
The purpose of this study is to determine whether the adipose-derived stem cells therapy is effective in the treatment of facial rejuvenation.
详细描述
This study will be a prospective study of patients who undergo adipose-derived stem cells therapy for facial rejuvenation at the hospital of Xuzhou medical university. The therapy involves injection of patient's own adipose-derived stem cells, which are separated from vacuumed fat obtained through liposuction of abdomen, hip, thigh and so on. It was confirmed the adipose-derived stem cells can be induced differentiation into fat cells, osteoblasts, chondrocytes, muscle cells, endothelial cells and so on under the corresponding condition in the current literature. The therapy has evolved as a less invasive technique for facial rejuvenation compared to more traditional techniques，such as fat cells injection, sodium hyaluronate injection. Through the use of pre and post treatment photos, three-dimensional skin CT, in addition to the therapeutic evaluation, patient satisfaction questionnaire and a clinician assessment, it is our hope that the investigators will confirm the rejuvenating capabilities of adipose-derived stem cells therapy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Males and females
- •Ages18-60
- •Patients of all racial and ethnic origins
- •Patients of all undergoing facial rejuvenation
排除标准
- •Ages under 18, and above 60
- •Female patients in pregnancy or menstrual period
- •Patients undergoing facial rejuvenation using other methods including botox injections, chemical peels, face lifts and others
- •Patients using blood thinners, aspirin and hormone, that cannot be stopped
- •Patients suffering with severe organic disease, such as coronary heart disease, hypertension, diabetes, lung dysfunction and so on
- •Patients suffering with mental disease, and acute or chronic infectious diseases
结局指标
主要结局
The therapeutic evaluation of adipose-derived stem cells or fat cells solely on facial rejuvenation
时间窗: 1,3 and 6 Months Post-Surgery
With the therapeutic evaluation of adipose-derived stem cells and fat cells solely on facial rejuvenation separately, which can reduce wrinkle and augment collagen of face skin. In order to assess the therapeutic effect, the investigators take face photos/make three-dimensional skin CT of face to evaluate the wrinkle and collagen before the therapy. Then take photos of face/ make three-dimensional skin CT of face to evaluate the wrinkle and collagen/ take patient satisfaction questionnaire and clinician assessment in 1 Months post-surgery. Take photos of face/ make three-dimensional skin CT of face/ take patient satisfaction questionnaire and clinician assessment in 3 Months post-surgery. Then take photos of face/ make three-dimensional skin CT of face to evaluate the wrinkle and collagen/ take patient satisfaction questionnaire and clinician assessment in 6 Months post-surgery. The investigators will summarize the therapeutic effect of facial rejuvenation based on the data.
次要结局
- The therapeutic evaluation of adipose-derived stem cells combined with fat cells on facial rejuvenation(1,3 and 6 Months Post-Surgery)
研究者
Jin Peisheng
Vice-President of the Affiliated Hospital of Xuzhou Medical College
Xuzhou Medical University