General risk factors and inflammatory determinants in younger patients with COPD

Franciscus Gasthuis en Vlietland0 个研究点目标入组 90 人开始时间: 待定最近更新: 2024年6月11日

适应症

试验速览

暂无简介。

•In order to be eligible to participate in this study, a subject must meet all of the following criteria:
•Inclusion criteria subjects with COPD
•Age between 40-80 years
•COPD gold II-IV; FEV 1< 80%
•Active or ex-smoker > 10 pack years
•Willing and able to comply with the study protocol
•COPD diagnosis is based on presence of airflow obstruction (post-bronchodilator spirometry FEV1/ FVC with z-score < -1.64)
•Inclusion criteria subjects without COPD
•Age between 40-80 years
•Willing and able to comply with the study protocol
•Active or ex-smoker > 10 pack years
•No COPD diagnosis, based on absence of airflow obstruction (post-bronchodilator spirometry FEV1/ FVC with z-score < -1.64)
•FEV1 > 80%
•Diffusing capacity > 70%

•A potential subject who meets any of the following criteria will be excluded from participation in this study:
•Exclusion criteria
•Not full comprehensive in the Dutch language.
•A liaison with the coordinating or principal investigator, which could likely influence the decision to participate in this study voluntarily (in concordance with the WMO – article 5)
•Other diseases which could influence pulmonary function and/or the immune system such as:
•o A possible infection of the upper- or lower respiratory tract 6 weeks prior to the collection of materials;
•o Active malignancy
•o Lung cancer diagnosis (also in the past)
•o (History or current) asthma diagnosis
•o Current pregnancy

发起方

Franciscus Gasthuis en Vlietland