Bronchoscopy Assisted Sampling of Cells and Fluid From the Lower Respiratory Tract of Human Subjects
Completed
- Conditions
- Respiratory Diseases
- Registration Number
- NCT00840723
- Lead Sponsor
- University of North Carolina, Chapel Hill
- Brief Summary
The purpose of this research study is to collect cells and liquid from the air passages of healthy adults, both smokers and non-smokers. These samples will be used for test-tube studies to explore mechanisms of diseases of the respiratory tract, and to compare the samples between people who smoke cigarettes and people who don't. Obtaining these samples requires an invasive procedure called "bronchoscopy".
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
- Current cigarette smokers
- Must be otherwise healthy with no chronic illness
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Exclusion Criteria
- Asthma
- Smoking related lung disease (including bronchitis)
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Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The goal of this project is to define the effect of smoking on key aspects of airway biology. These studies will also provide crucial & novel definition of airway biology in smokers against which COPD & CF patients will be compared. At the time of bronchoscopy
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
UNC Center for Environmental Medicine, Asthma and Lung Biology
🇺🇸Chapel Hill, North Carolina, United States