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Akershus University Hospital Retrospective Cohort Study of Family Based Treatment

Conditions
Atypical Anorexia Nervosa
Anorexia Nervosa
Interventions
Behavioral: Non-manualised family therapy.
Behavioral: Family Based Treatment
Registration Number
NCT05748457
Lead Sponsor
University Hospital, Akershus
Brief Summary

The goal of this observational study is to compare short and long-term effects of manualised Family Based Treatment for adolescent anorexia nervosa to those of non-manualised family therapy. The study will approach former patients who were treated before and after Family Based Therapy was adopted in an outpatient clinic, and extract data from electronic health records and public registries.

Detailed Description

A two-group retrospective exploratory cohort study with longitudinal follow-up comparing adolescents with anorexia nervosa treated with generic family therapy to those treated with the manualised Family Based Treatment (FBT). The primary aim is to investigate whether adoption of FBT has led to faster normalisation of weight and lower rates of eating disorder in early adulthood. Secondary aims are to investigate whether implementation of FBT has changed the time to discharge, heterogeneity of patient weight change across treatment, rates of adverse events, rates of readmission, patient experiences of the treatment, long term functional outcomes and mortality. Data are extracted from patient health records, reported by participants and extracted from public registries.

Recruitment & Eligibility

Status
ENROLLING_BY_INVITATION
Sex
All
Target Recruitment
175
Inclusion Criteria

• Clinical diagnosis of F50.0 Anorexia nervosa or F50.1 Atypical anorexia nervosa according to the International Classification of Diseases-10.

Exclusion Criteria

• Patient was treated during the years 2018-2020 and FBT was never initiated according to patient health records.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
2015-2017Non-manualised family therapy.Patients treated for anorexia nervosa in the years 2015-2017 at Nedre Romerike outpatient clinic, Department of child and adolescent mental health services, Akershus university hospital.
2018-2020Family Based TreatmentPatients treated for anorexia nervosa in the years 2018-2020 at Nedre Romerike outpatient clinic, Department of child and adolescent mental health services, Akershus university hospital.
Primary Outcome Measures
NameTimeMethod
Time to weight restorationAssessed retrospectively at enrolment.

Number of days from start of treatment to a weight measurement placing the patient at or above 95% of expected body weight (50. percentile) for age and sex given Norwegian population norms.

Secondary Outcome Measures
NameTimeMethod
Time to discharge from treatmentAssessed retrospectively at enrolment.

Number of days from start of treatment to the date of discharge from the outpatient clinic.

Treatment for eating disorder in adulthoodAssessed 5, 10, 15 and 20 years post treatment.

Treatment in specialist mental health services for any eating disorder.

MortalityAssessed 5, 10, 15 and 20 years post treatment.

Death from any cause.

Employment status and welfare benefitsAssessed 5, 10, 15 and 20 years post treatment.

Employment status or receipt of welfare benefits, obtained from national registries.

Time to readmission to treatmentAssessed retrospectively at enrolment.

Number of days from start of treatment to any date of readmission to the outpatient clinic.

Level of educationAssessed 5, 10, 15 and 20 years post treatment.

Highest level of education achieved, obtained from national registries.

Trial Locations

Locations (1)

Nedre Romerike BUP

🇳🇴

Lillestrøm, Norway

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