Dilution of ropivacaine by saline can decrease its dose requirement in spinal anesthesia for cesarean sectio
Not Applicable
Completed
- Conditions
- Elective cesarean deliveryPregnancy and Childbirth
- Registration Number
- ISRCTN45576750
- Lead Sponsor
- 6th Affiliated Hospital to Shanghai Jiaotong University (China)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 60
Inclusion Criteria
1. American Society of Anesthesiologists (ASA) physical status I to II
2. Undergoing elective cesarean delivery
3. No contraindications to subarachnoid anesthesia
Exclusion Criteria
1. Allergic to local anesthetics
2. Emergent cesarean deliveries
3. Body mass index (BMI) < 22 or >30
4. Hypertensive disorders
5. Peripartum hemorrhagic conditions
6. Neurologic, cardiac or hematologic diseases
7. Diabetes
8. Eclampsia
9. Fetal distress, or known fetal anomalies
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Effective Dose 50 (ED50) of ropivacaine for intrathecal administration<br>2. The rate of adequate anesthesia
- Secondary Outcome Measures
Name Time Method 1. Heart rate<br>2. Systolic, diastolic, and mean arterial blood pressure<br>3. Hemoglobin oxygen saturation