跳至主要内容
临床试验/NCT05335837
NCT05335837Unknown不适用

Postoperative Recovery Time in Inguinal Hernia Repair Under Ilioinguinal, Iliohypogastric Nerve Block and Sedation Versus General Anesthesia: a Propensity Score Matched-cohort Retrospective Study

Lawson Health Research Institute1 个研究点 分布在 1 个国家目标入组 350 人开始时间: 2022年5月1日最近更新:
适应症

试验速览

阶段
不适用
入组人数
350
试验地点
1
主要终点
Postoperative recovery time

研究概览

简要总结

Inguinal hernia have traditionally been done under general anesthesia. While safe, general anesthesia is associated with potential postoperative nausea/vomiting and drowsiness. Additionally, the recent COVID19 pandemic has heightened the precaution to avoid aerosol generating procedures (AGP) if possible. General anesthesia requires airway manipulation, thus necessitate performing an AGP. Recently, we began using peripheral nerve block and sedation as primary anesthetic technique for inguinal hernia repairs. While surgeon administered local anesthetic, also known as local infiltration, has been done for inguinal hernia repair, using specific nerve blocks and sedation has not been compared with general anesthesia. We believe the advantage of this novel technique can improve postoperative recovery. This retrospective study will compare the total hospital length of stay of those receiving nerve blocks and sedation as primary anesthetic techniques versus those with general anesthesia.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 18 years or older
  • American Society of Anesthesiologists (ASA) Physical Status I to III
  • Body Mass Index (BMI) less than 45
  • Single hernia repair, elective, ambulatory surgery

排除标准

  • Opioid dependence (30 mg oral morphine equivalents daily or more)
  • History of malignant hyperthermia
  • Pregnancy

结局指标

主要结局

Postoperative recovery time

时间窗: Time from exiting operating room to time ready for hospital discharge, up to 100 hours

Time from exiting operating room to time ready for hospital discharge

次要结局

  • Desaturation(Time from exiting operating room to time ready for hospital discharge, up to 100 hours)
  • Postoperative opioid dose(Time from exiting operating room to time ready for hospital discharge, up to 100 hours)
  • Hospital length of stay(Time from patient registration to ready for hospital discharge, up to 100 hours)
  • Severe pain(Time from exiting operating room to time ready for hospital discharge, up to 100 hours)
  • Preoperative time(Time from patient registration to entering operating room, up to 100 hours)
  • Postoperative nausea vomiting(Time from exiting operating room to time ready for hospital discharge, up to 100 hours)
  • Intraoperative time(Time from entering to exiting operating room, up to 100 hours)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Cheng Lin

Clinical Professor

Lawson Health Research Institute

研究点 (1)

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